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1BC7
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SERUM RESPONSE FACTOR ACCESSORY PROTEIN 1A (SAP-1)/DNA COMPLEX
分子名称: DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*TP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*AP*GP*GP*AP*TP*GP*TP*G)-3'), PROTEIN (ETS-DOMAIN PROTEIN)
著者Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R.
登録日1998-05-05
公開日1999-01-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.
Mol.Cell, 2, 1998
4CO8
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BU of 4co8 by Molmil
Structure of the DNA binding ETS domain of human ETV4
分子名称: 1,2-ETHANEDIOL, ETS TRANSLOCATION VARIANT 4
著者Newman, J.A, Cooper, C.D.O, Shrestha, L, Burgess-Brown, N, Kopec, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O.
登録日2014-01-27
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
J.Biol.Chem., 290, 2015
5YBC
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X-ray structure of native ETS-domain domain of Ergp55
分子名称: GLYCEROL, Transcriptional regulator ERG
著者Saxena, A.K, Gangwar, S.P.
登録日2017-09-04
公開日2018-09-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun, 74, 2018
1BC8
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STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS
分子名称: DNA (5'-D(*AP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), PROTEIN (SAP-1 ETS DOMAIN), ...
著者Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R.
登録日1998-05-05
公開日1998-12-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.
Mol.Cell, 2, 1998
5YBD
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BU of 5ybd by Molmil
X-ray structure of ETS domain of Ergp55 in complex with E74DNA
分子名称: DNA (5'-D(P*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), Transcriptional regulator ERG
著者Saxena, A.K, Gangwar, S.P.
登録日2017-09-04
公開日2018-11-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.769 Å)
主引用文献Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun, 74, 2018
1GVJ
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BU of 1gvj by Molmil
ETS-1 DNA BINDING AND AUTOINHIBITORY DOMAINS
分子名称: C-ETS-1 PROTEIN
著者Tahirov, T.H, Ogata, K.
登録日2002-02-14
公開日2004-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Crystal Structure of C-Ets-1 DNA-Binding and Autoinhibitory Domains
To be Published
5ILS
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BU of 5ils by Molmil
Autoinhibited ETV1
分子名称: ETS translocation variant 1
著者Whitby, F.G, Currie, S.L.
登録日2016-03-04
公開日2017-02-22
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.399 Å)
主引用文献Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Nucleic Acids Res., 45, 2017
5ILV
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Uninhibited ETV5
分子名称: ETS translocation variant 5
著者Whitby, F.G, Currie, S.L.
登録日2016-03-04
公開日2017-02-22
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Nucleic Acids Res., 45, 2017
5ILU
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BU of 5ilu by Molmil
Autoinhibited ETV4
分子名称: ETS translocation variant 4
著者Whitby, F.G, Currie, S.L.
登録日2016-03-04
公開日2017-02-22
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.101 Å)
主引用文献Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Nucleic Acids Res., 45, 2017
8SP1
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BU of 8sp1 by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGIAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2023-05-01
公開日2023-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SMJ
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Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAATGGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2023-04-26
公開日2023-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SMH
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BU of 8smh by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2023-04-26
公開日2023-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8T9U
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BU of 8t9u by Molmil
Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2023-06-26
公開日2023-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
2LF7
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BU of 2lf7 by Molmil
Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to Q436
分子名称: Transcription factor ETV6
著者Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P.
登録日2011-06-28
公開日2012-05-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain.
J.Mol.Biol., 421, 2012
2LF8
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BU of 2lf8 by Molmil
Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to R458
分子名称: Transcription factor ETV6
著者Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P.
登録日2011-06-28
公開日2012-05-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain.
J.Mol.Biol., 421, 2012
2MD5
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BU of 2md5 by Molmil
Structure of uninhibited ETV6 ETS domain
分子名称: Transcription factor ETV6
著者De, S, Mcintosh, L.P, Chan, A.C, Coyne, H.J, Okon, M, Graves, B.J, Murphy, M.E.
登録日2013-08-29
公開日2013-12-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
2NNY
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BU of 2nny by Molmil
Crystal structure of the Ets1 dimer DNA complex.
分子名称: 5'-D(*A*CP*TP*CP*CP*AP*GP*GP*AP*AP*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*TP*CP*T)-3', 5'-D(*T*AP*GP*AP*CP*AP*GP*GP*AP*AP*GP*CP*AP*CP*TP*TP*CP*CP*TP*GP*GP*AP*G)-3', C-ets-1 protein
著者Lamber, E.P, Kachalova, G.S, Wilmanns, M.
登録日2006-10-24
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization.
Embo J., 27, 2008
6VG2
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BU of 6vg2 by Molmil
Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with 16-mer DNA CAGAGGATGTGGCTTC
分子名称: DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*GP*CP*TP*TP*C)-3'), Friend leukemia integration 1 transcription factor
著者Hou, C, Tsodikov, O.V.
登録日2020-01-07
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
Structure, 29, 2021
1K7A
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BU of 1k7a by Molmil
Ets-1(331-440)+GGAG duplex
分子名称: C-ets-1 Protein, DNA (5'-D(*CP*AP*CP*AP*TP*CP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*GP*AP*TP*GP*T)-3')
著者Garvie, C.W, Hagman, J, Wolberger, C.
登録日2001-10-18
公開日2002-01-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K79
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Ets-1(331-440)+GGAA duplex
分子名称: C-ets-1 protein, DNA (5'-D(*CP*AP*CP*AP*TP*TP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*AP*AP*TP*GP*T)-3')
著者Garvie, C.W, Hagman, J, Wolberger, C.
登録日2001-10-18
公開日2002-01-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1MD0
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BU of 1md0 by Molmil
CRYSTAL STRUCTURE OF AN INHIBITED FRAGMENT OF Ets-1
分子名称: C-ets-1 protein
著者Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
登録日2002-08-06
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships
J.Biol.Chem., 277, 2002
4IRG
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BU of 4irg by Molmil
Uninhibited DNA-binding domain of the Ets transcription factor ERG
分子名称: Transcriptional regulator ERG
著者Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H.
登録日2013-01-14
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IRH
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BU of 4irh by Molmil
Auto-inhibited ERG Ets domain
分子名称: Transcriptional regulator ERG
著者Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H.
登録日2013-01-14
公開日2013-07-31
最終更新日2013-08-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IRI
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BU of 4iri by Molmil
Auto-inhibited ERG Ets Domain-DNA Complex
分子名称: DNA (5'-D(*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*G)-3'), Transcriptional regulator ERG
著者Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H.
登録日2013-01-14
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
4MHG
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BU of 4mhg by Molmil
Crystal structure of ETV6 bound to a specific DNA sequence
分子名称: Complementary Specific 14 bp DNA, Specific 14 bp DNA, Transcription factor ETV6
著者Chan, A.C, De, S, Coyne III, H.J, Okon, M, Murphy, M.E, Graves, B.J, McIntosh, L.P.
登録日2013-08-29
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014

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