1BC8

STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS

Summary for 1BC8

DescriptorDNA (5'-D(*TP*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), DNA (5'-D(*AP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), PROTEIN (SAP-1 ETS DOMAIN), ... (5 entities in total)
Functional Keywordsets domain, dna-binding domain, winged helix-turn-helix, dna-binding specificity, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P28324
Total number of polymer chains3
Total molecular weight17439.04
Authors
Mo, Y.,Vaessen, B.,Johnston, K.,Marmorstein, R. (deposition date: 1998-05-05, release date: 1998-12-01, Last modification date: 2011-07-13)
Primary citation
Mo, Y.,Vaessen, B.,Johnston, K.,Marmorstein, R.
Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.
Mol.Cell, 2:201-212, 1998
PubMed: 9734357 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(00)80130-6
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.93 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers16011.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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