8SP1

Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGIAAGTGGG)

Summary for 8SP1

• Entry DOI: 10.2210/pdb8sp1/pdb
• Related: 8SMH 8SMJ
• Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1, ... (5 entities in total)
• Functional Keywords: transcription factor, protein-dna complex, ets family, ets, pu.1, transcription-dna complex, transcription, transcription/dna
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 21437.01

Authors

Terrell, J.R.,Poon, G.M.K. (deposition date: 2023-05-01, release date: 2023-11-29, Last modification date: 2024-01-17)

• Primary citation: Vernon, T.N.,Terrell, J.R.,Albrecht, A.V.,Germann, M.W.,Wilson, W.D.,Poon, G.M.K.; Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.; Structure, 32:83-96.e4, 2024; PubMed: 38042148; DOI: 10.1016/j.str.2023.11.003

Experimental method

X-RAY DIFFRACTION (1.62 Å)