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7U46
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BU of 7u46 by Molmil
Cryo-EM structure of CENP-A nucleosome (palindromic alpha satellite DNA) in complex with CENP-N
Descriptor: Centromere protein N, DNA (147-MER), Histone H2A, ...
Authors:Zhou, K, Luger, K.
Deposit date:2022-02-28
Release date:2022-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:CENP-N promotes the compaction of centromeric chromatin.
Nat.Struct.Mol.Biol., 29, 2022
7U47
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BU of 7u47 by Molmil
CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and palindromic alpha satellite DNA sequence
Descriptor: Centromere protein N, DNA (147-MER), Histone H2A, ...
Authors:Zhou, K, Luger, K.
Deposit date:2022-02-28
Release date:2022-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:CENP-N promotes the compaction of centromeric chromatin.
Nat.Struct.Mol.Biol., 29, 2022
7U4D
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BU of 7u4d by Molmil
CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and 601 DNA sequence
Descriptor: Centromere protein N, DNA (147-MER), Histone H2A, ...
Authors:Zhou, K, Luger, K.
Deposit date:2022-02-28
Release date:2022-03-30
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:CENP-N promotes the compaction of centromeric chromatin.
Nat.Struct.Mol.Biol., 29, 2022
5GT3
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BU of 5gt3 by Molmil
Crystal structure of nucleosome particle in the presence of human testis-specific histone variant, hTh2b
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-D, ...
Authors:Kumarevel, T, Sivaraman, P.
Deposit date:2016-08-18
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
7U51
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BU of 7u51 by Molmil
Nucleosome core particle with AP-site at SHL-6
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ...
Authors:Freudenthal, B.D, Weaver, T.M.
Deposit date:2022-03-01
Release date:2022-09-07
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
7U52
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BU of 7u52 by Molmil
nucleosome core particle with AP-site at SHL-6.5
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ...
Authors:Freudenthal, B.D, Weaver, T.M.
Deposit date:2022-03-01
Release date:2022-09-07
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
7U50
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BU of 7u50 by Molmil
APE1 bound to a nucleosome core particle with AP-site at SHL-6
Descriptor: DNA (144-MER), DNA (145-MER), DNA-(apurinic or apyrimidinic site) endonuclease, ...
Authors:Weaver, T.M, Freudenthal, B.D.
Deposit date:2022-03-01
Release date:2022-09-07
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
4J8W
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BU of 4j8w by Molmil
X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)osmium(II)
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-02-15
Release date:2013-04-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
6OM3
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BU of 6om3 by Molmil
Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle
Descriptor: DNA (146-MER), DNA (147-MER), Histone H2A, ...
Authors:De Ioannes, P.E, Wang, M, Armache, K.-J.
Deposit date:2019-04-18
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and function of the Orc1 BAH-nucleosome complex.
Nat Commun, 10, 2019
5HQ2
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BU of 5hq2 by Molmil
Structural model of Set8 histone H4 Lys20 methyltransferase bound to nucleosome core particle
Descriptor: DNA (149-MER), Guanine nucleotide exchange factor SRM1, Histone H2A, ...
Authors:Tavarekere, G, McGinty, R.K, Tan, S.
Deposit date:2016-01-21
Release date:2016-03-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate.
J.Mol.Biol., 428, 2016
6PA7
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BU of 6pa7 by Molmil
The cryo-EM structure of the human DNMT3A2-DNMT3B3 complex bound to nucleosome.
Descriptor: CHLORIDE ION, DNA (167-MER), DNA (cytosine-5)-methyltransferase 3A, ...
Authors:Xu, T.H, Liu, M, Zhou, X.E, Liang, G, Zhao, G, Xu, H.E, Melcher, K, Jones, P.A.
Deposit date:2019-06-11
Release date:2020-06-17
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B.
Nature, 586, 2020
4JJN
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BU of 4jjn by Molmil
Crystal structure of heterochromatin protein Sir3 in complex with a silenced yeast nucleosome
Descriptor: DNA (146-MER), Histone H2A.2, Histone H2B.2, ...
Authors:Wang, F, Li, G, Mohammed, A, Lu, C, Currie, M, Johnson, A, Moazed, D.
Deposit date:2013-03-08
Release date:2013-05-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA.
Proc.Natl.Acad.Sci.USA, 110, 2013
6PWW
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BU of 6pww by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome
Descriptor: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
Deposit date:2019-07-23
Release date:2019-12-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
6PWF
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BU of 6pwf by Molmil
Cryo-EM structure of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome
Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ...
Authors:Chittori, S, Subramaniam, S.
Deposit date:2019-07-22
Release date:2019-08-21
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome.
Nucleic Acids Res., 47, 2019
6PX1
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BU of 6px1 by Molmil
Set2 bound to nucleosome
Descriptor: DNA (149-MER), Histone H2B 1.1, Histone H3, ...
Authors:Halic, M, Bilokapic, S.
Deposit date:2019-07-24
Release date:2019-08-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Nucleosome and ubiquitin position Set2 to methylate H3K36.
Nat Commun, 10, 2019
4KUD
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BU of 4kud by Molmil
Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast nucleosome core particle
Descriptor: Histone H2A.2, Histone H2B.1, Histone H3, ...
Authors:Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Nat.Struct.Mol.Biol., 20, 2013
6PWX
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BU of 6pwx by Molmil
Cryo-EM structure of RbBP5 bound to the nucleosome
Descriptor: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
Deposit date:2019-07-23
Release date:2019-12-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
4KHA
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BU of 4kha by Molmil
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Histone H2A, ...
Authors:Hondele, M, Halbach, F, Hassler, M, Ladurner, A.G.
Deposit date:2013-04-30
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis of histone H2A-H2B recognition by the essential chaperone FACT.
Nature, 499, 2013
4KGC
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BU of 4kgc by Molmil
Nucleosome Core Particle Containing (ETA6-P-CYMENE)-(1, 2-ETHYLENEDIAMINE)-RUTHENIUM
Descriptor: (ethane-1,2-diamine-kappa~2~N,N')[(1,2,3,4,5,6-eta)-1-methyl-4-(propan-2-yl)cyclohexane-1,2,3,4,5,6-hexayl]ruthenium, DNA (145-mer), Histone H2A, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-04-29
Release date:2014-03-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity
Nat Commun, 5, 2014
6PX3
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BU of 6px3 by Molmil
Set2 bound to nucleosome
Descriptor: DNA (145-MER), Histone H2B 1.1, Histone H3, ...
Authors:Halic, M, Bilokapic, S.
Deposit date:2019-07-24
Release date:2019-08-28
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Nucleosome and ubiquitin position Set2 to methylate H3K36.
Nat Commun, 10, 2019
5G2E
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BU of 5g2e by Molmil
Structure of the Nap1 H2A H2B complex
Descriptor: HISTONE H2A TYPE 1, HISTONE H2B 1.1, NUCLEOSOME ASSEMBLY PROTEIN
Authors:AguilarGurrieri, C, Larabi, A, Vinayachandran, V, Patel, N.A, Yen, K, Reja, R, Ebong, I.O, Schoehn, G, Robinson, C.V, Pugh, B.F, Panne, D.
Deposit date:2016-04-07
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (6.7 Å)
Cite:Structural Evidence for Nap1-Dependent H2A-H2B Deposition and Nucleosome Assembly.
Embo J., 35, 2016
5GT0
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BU of 5gt0 by Molmil
Crystal structure of nucleosome complex with human testis-specific histone variants, Th2a
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ...
Authors:Kumarevel, T, Sivaraman, P.
Deposit date:2016-08-18
Release date:2017-02-15
Last modified:2022-05-04
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
4J8X
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BU of 4j8x by Molmil
X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)ruthenium(II)
Descriptor: DNA, Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-02-15
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
4J8U
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BU of 4j8u by Molmil
X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)osmium(II)
Descriptor: DNA, Histone H2A type 1, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-02-15
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
4LD9
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BU of 4ld9 by Molmil
Crystal structure of the N-terminally acetylated BAH domain of Sir3 bound to the nucleosome core particle
Descriptor: Histone H2A, Histone H2B 1.1, Histone H3.2, ...
Authors:Arnaudo, N, Fernandez, I.S, McLaughlin, S.H, Peak-Chew, S.Y, Rhodes, D, Martino, F.
Deposit date:2013-06-24
Release date:2013-08-14
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (3.306 Å)
Cite:The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle.
Nat.Struct.Mol.Biol., 20, 2013

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數據於2024-05-08公開中

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