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8EH5
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BU of 8eh5 by Molmil
Cryo-EM structure of L9 Fab in complex with rsCSP
Descriptor: Circumsporozoite protein, L9 Heavy chain, L9 Light chain
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-09-13
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.
Nat Commun, 14, 2023
8EKA
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BU of 8eka by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(class 2)
Descriptor: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-09-20
Release date:2023-03-15
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
8EK1
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BU of 8ek1 by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(dominant class)
Descriptor: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-09-19
Release date:2023-03-15
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
8DYX
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BU of 8dyx by Molmil
Cryo-EM structure of 311 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 311 heavy chain, 311 light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-05
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DYY
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BU of 8dyy by Molmil
Cryo-EM structure of 334 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 334 Fab heavy chain, 334 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-05
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DYW
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BU of 8dyw by Molmil
Cryo-EM structure of 239 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 239 Fab heavy chain, 239 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-05
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ5
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BU of 8dz5 by Molmil
Cryo-EM structure of 364 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 364 Fab heavy chain, 364 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-06
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ4
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BU of 8dz4 by Molmil
Cryo-EM structure of 356 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 356 Fab heavy chain, 356 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-06
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ3
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BU of 8dz3 by Molmil
Cryo-EM structure of 337 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 337 Fab heavy chain, 337 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-06
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
7B26
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BU of 7b26 by Molmil
CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3
Descriptor: CirpA1, Properdin, alpha-D-mannopyranose, ...
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
2RJQ
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BU of 2rjq by Molmil
Crystal structure of ADAMTS5 with inhibitor bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, ADAMTS-5, ...
Authors:Mosyak, L, Stahl, M, Somers, W.
Deposit date:2007-10-15
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein Sci., 17, 2008
4OKU
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BU of 4oku by Molmil
Structure of Toxoplasma gondii proMIC2
Descriptor: Micronemal protein MIC2, alpha-D-mannopyranose
Authors:Song, G, Springer, T.A.
Deposit date:2014-01-22
Release date:2014-03-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of the Toxoplasma gliding motility adhesin.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OKR
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BU of 4okr by Molmil
Structures of Toxoplasma gondii MIC2
Descriptor: Micronemal protein MIC2, alpha-D-mannopyranose
Authors:Song, G, Springer, T.A.
Deposit date:2014-01-22
Release date:2014-03-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structures of the Toxoplasma gliding motility adhesin.
Proc.Natl.Acad.Sci.USA, 111, 2014
3GHM
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BU of 3ghm by Molmil
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ...
Authors:Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
3GHN
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BU of 3ghn by Molmil
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ...
Authors:Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
5FTT
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BU of 5ftt by Molmil
Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADHESION G PROTEIN-COUPLED RECEPTOR L3, CALCIUM ION, ...
Authors:Jackson, V.A, Mehmood, S, Chavent, M, Roversi, P, Carrasquero, M, del Toro, D, Seyit-Bremer, G, Ranaivoson, F.M, Comoletti, D, Sansom, M.S.P, Robinson, C.V, Klein, R, Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
5FOE
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BU of 5foe by Molmil
Crystal structure of the C. elegans Protein O-fucosyltransferase 2 (CePOFUT2) double mutant (R298K-R299K) in complex with GDP and the human TSR1 from thrombospondin 1
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP-fucose protein O-fucosyltransferase 2,Thrombospondin-1, ...
Authors:Valero-Gonzalez, J, Leonhard-Melief, C, Lira-Navarrete, E, Jimenez-Oses, G, Hernandez-Ruiz, C, Pallares, M.C, Yruela, I, Vasudevan, D, Lostao, A, Corzana, F, Takeuchi, H, Haltiwanger, R.S, Hurtado-Guerrero, R.
Deposit date:2015-11-19
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:A Proactive Role of Water Molecules in Acceptor Recognition of Thrombospondin Type 1 Repeats by Protein-O-Fucosyltransferase 2
Nat.Chem.Biol., 12, 2016
6MB3
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BU of 6mb3 by Molmil
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
Descriptor: Fab311 heavy chain, Fab311 light chain, Plasmodium falciparum recombinant shortened CSP
Authors:Cottrell, C.A, Torres, J.L, Ward, A.B.
Deposit date:2018-08-29
Release date:2018-10-31
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts.
Sci Adv, 4, 2018
6MHG
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BU of 6mhg by Molmil
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
Descriptor: Fab311 heavy chain, Fab311 light chain, circumsporozoite protein
Authors:Cottrell, C.A, Torres, J.L, Ward, A.B.
Deposit date:2018-09-17
Release date:2018-10-31
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts.
Sci Adv, 4, 2018
6OOL
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BU of 6ool by Molmil
Structural elucidation of the Ectodomain of mouse UNC5H2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Netrin receptor UNC5B, ...
Authors:Stetefeld, J, McDougall, M.D, Loewen, P.C, Moya, A, Meier, M.
Deposit date:2019-04-23
Release date:2020-04-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural elucidation of the Ectodomain of mouse UNC5H2
To be published
1W0S
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BU of 1w0s by Molmil
Solution structure of trimeric form of properdin by X-ray solution scattering and analytical ultracentrifugation
Descriptor: PROPERDIN
Authors:Sun, Z, Reid, K.B.M, Perkins, S.J.
Deposit date:2004-06-09
Release date:2005-07-06
Last modified:2024-05-08
Method:SOLUTION SCATTERING
Cite:The Dimeric and Trimeric Solution Structures of the Multidomain Complement Protein Properdin by X-Ray Scattering, Analytical Ultracentrifugation and Constrained Modelling.
J.Mol.Biol., 343, 2004
4HQO
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BU of 4hqo by Molmil
Crystal structure of Plasmodium vivax TRAP protein
Descriptor: CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ...
Authors:Song, G, Koksal, A.C, Lu, C, Springer, T.A.
Deposit date:2012-10-25
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
1W0R
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BU of 1w0r by Molmil
Solution structure of dimeric form of properdin by X-ray solution scattering and analytical ultracentrifugation
Descriptor: PROPERDIN
Authors:Sun, Z, Reid, K.B.M, Perkins, S.J.
Deposit date:2004-06-09
Release date:2005-07-06
Last modified:2024-05-08
Method:SOLUTION SCATTERING
Cite:The Dimeric and Trimeric Solution Structures of the Multidomain Complement Protein Properdin by X-Ray Scattering, Analytical Ultracentrifugation and Constrained Modelling.
J.Mol.Biol., 343, 2004
4HQL
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BU of 4hql by Molmil
Crystal structure of magnesium-loaded Plasmodium vivax TRAP protein
Descriptor: CHLORIDE ION, MAGNESIUM ION, Sporozoite surface protein 2, ...
Authors:Song, G, Koksal, A.C, Lu, C, Springer, T.A.
Deposit date:2012-10-25
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.241 Å)
Cite:Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
4HQN
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BU of 4hqn by Molmil
Crystal structure of manganese-loaded Plasmodium vivax TRAP protein
Descriptor: CHLORIDE ION, MANGANESE (II) ION, Sporozoite surface protein 2, ...
Authors:Song, G, Koksal, A.C, Lu, C, Springer, T.A.
Deposit date:2012-10-25
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012

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数据于2024-05-15公开中

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