8DYW

Cryo-EM structure of 239 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)

Summary for 8DYW

Entry DOI	10.2210/pdb8dyw/pdb
EMDB information	27784
Descriptor	Circumsporozoite protein, 239 Fab light chain, 239 Fab heavy chain (3 entities in total)
Functional Keywords	malaria antibody, pfcsp, immune system
Biological source	Plasmodium falciparum More
Total number of polymer chains	21
Total formula weight	762681.92
Authors	Martin, G.M.,Ward, A.B. (deposition date: 2022-08-05, release date: 2023-08-02, Last modification date: 2024-04-24)
Primary citation	Martin, G.M.,Torres, J.L.,Pholcharee, T.,Oyen, D.,Flores-Garcia, Y.,Gibson, G.,Moskovitz, R.,Beutler, N.,Jung, D.D.,Copps, J.,Lee, W.H.,Gonzalez-Paez, G.,Emerling, D.,MacGill, R.S.,Locke, E.,King, C.R.,Zavala, F.,Wilson, I.A.,Ward, A.B. Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection. Nat Commun, 14:4546-4546, 2023 Cited by PubMed: 37507365 DOI: 10.1038/s41467-023-40151-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.72 Å)

Structure validation