8DZ5

Cryo-EM structure of 364 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)

Summary for 8DZ5

Entry DOI	10.2210/pdb8dz5/pdb
EMDB information	27789
Descriptor	Circumsporozoite protein, 364 Fab heavy chain, 364 Fab light chain (3 entities in total)
Functional Keywords	malaria antibody, pfcsp, immune system
Biological source	Plasmodium falciparum More
Total number of polymer chains	11
Total formula weight	266536.12
Authors	Martin, G.M.,Ward, A.B. (deposition date: 2022-08-06, release date: 2023-08-02, Last modification date: 2024-04-24)
Primary citation	Martin, G.M.,Torres, J.L.,Pholcharee, T.,Oyen, D.,Flores-Garcia, Y.,Gibson, G.,Moskovitz, R.,Beutler, N.,Jung, D.D.,Copps, J.,Lee, W.H.,Gonzalez-Paez, G.,Emerling, D.,MacGill, R.S.,Locke, E.,King, C.R.,Zavala, F.,Wilson, I.A.,Ward, A.B. Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection. Nat Commun, 14:4546-4546, 2023 Cited by PubMed: 37507365 DOI: 10.1038/s41467-023-40151-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.84 Å)

Structure validation