3KXV
 
 | | Structure of complement Factor H variant Q1139A | | 分子名称: | Complement factor H, SULFATE ION | | 著者 | Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. | | 登録日 | 2009-12-04 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | | 主引用文献 | Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
Mol.Immunol., 47, 2010
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3IU3
 | | Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain | | 分子名称: | Heavy chain of Fab fragment of Basiliximab, Interleukin-2 receptor alpha chain, Light chain of Fab fragment of Basiliximab, ... | | 著者 | Du, J, Yang, H, Wang, J, Ding, J. | | 登録日 | 2009-08-29 | | 公開日 | 2010-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab
J.Immunol., 184, 2010
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3INB
 | | Structure of the measles virus hemagglutinin bound to the CD46 receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein, Membrane cofactor protein, ... | | 著者 | Santiago, C, Celma, M.L, Stehle, T, Casasnovas, J.M. | | 登録日 | 2009-08-12 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the measles virus hemagglutinin bound to the CD46 receptor
Nat.Struct.Mol.Biol., 17, 2010
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2KMS
 | | Combined high- and low-resolution techniques reveal compact structure in central portion of factor H despite long inter-modular linkers | | 分子名称: | Complement factor H | | 著者 | Schmidt, C.Q, Herbert, A.P, Guariento, M, Mertens, H.D.T, Soares, D.C, Uhrin, D, Rowe, A.J, Svergun, D.I, Barlow, P.N. | | 登録日 | 2009-08-04 | | 公開日 | 2009-11-03 | | 最終更新日 | 2020-02-26 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module
J.Mol.Biol., 395, 2010
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3HRZ
 | | Cobra Venom Factor (CVF) in complex with human factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | | 登録日 | 2009-06-10 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Embo J., 28, 2009
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3HS0
 | | Cobra Venom Factor (CVF) in complex with human factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | | 登録日 | 2009-06-10 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Embo J., 28, 2009
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2WII
 | | Complement C3b in complex with factor H domains 1-4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ... | | 著者 | Wu, J, Janssen, B.J.C, Gros, P. | | 登録日 | 2009-05-12 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat. Immunol., 10, 2009
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3GOV
 | | Crystal structure of the catalytic region of human MASP-1 | | 分子名称: | GLYCEROL, MASP-1 | | 著者 | Harmat, V, Dobo, J, Beinrohr, L, Sebestyen, E, Zavodszky, P, Gal, P. | | 登録日 | 2009-03-20 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity.
J.Immunol., 183, 2009
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3GAU
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3GAV
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3GAW
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2W80
 | | Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H | | 分子名称: | COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN | | 著者 | Schneider, M.C, Prosser, B.E, Caesar, J.J.E, Kugelberg, E, Li, S, Zhang, Q, Quoraishi, S, Lovett, J.E, Deane, J.E, Sim, R.B, Roversi, P, Johnson, S, Tang, C.M, Lea, S.M. | | 登録日 | 2009-01-08 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
Nature, 458, 2009
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2W81
 | | Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H | | 分子名称: | COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN | | 著者 | Schneider, M.C, Prosser, B.E, Caesar, J.J.E, Kugelberg, E, Li, S, Zhang, Q, Quoraishi, S, Lovett, J.E, Deane, J.E, Sim, R.B, Roversi, P, Johnson, S, Tang, C.M, Lea, S.M. | | 登録日 | 2009-01-08 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
Nature, 458, 2009
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3ERB
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2QZH
 | | SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF | | 分子名称: | Complement decay-accelerating factor | | 著者 | Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G. | | 登録日 | 2007-08-16 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (14 Å) | | 主引用文献 | Interaction of decay-accelerating factor with coxsackievirus b3.
J.Virol., 81, 2007
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2QZF
 | | SCR1 of DAF from 1ojv fitted into cryoEM density | | 分子名称: | Complement decay-accelerating factor | | 著者 | Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G. | | 登録日 | 2007-08-16 | | 公開日 | 2007-10-30 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (14 Å) | | 主引用文献 | Interaction of decay-accelerating factor with coxsackievirus b3.
J.Virol., 81, 2007
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2QZD
 | | Fitted structure of SCR4 of DAF into cryoEM density | | 分子名称: | Complement decay-accelerating factor | | 著者 | Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G. | | 登録日 | 2007-08-16 | | 公開日 | 2007-10-30 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (14 Å) | | 主引用文献 | Interaction of decay-accelerating factor with coxsackievirus b3.
J.Virol., 81, 2007
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2QY0
 | | Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts | | 分子名称: | Complement C1r subcomponent, GLYCEROL | | 著者 | Kardos, J, Harmat, V, Pallo, A, Barabas, O, Szilagyi, K, Graf, L, Naray-Szabo, G, Goto, Y, Zavodszky, P, Gal, P. | | 登録日 | 2007-08-13 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r.
Mol.Immunol., 45, 2008
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2V8E
 | | Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, CHLORIDE ION, COMPLEMENT FACTOR H, ... | | 著者 | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Tarelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | | 登録日 | 2007-08-07 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration.
J.Exp.Med., 204, 2007
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2RLQ
 | | NMR structure of CCP modules 2-3 of complement factor H | | 分子名称: | Complement factor H | | 著者 | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | | 登録日 | 2007-07-29 | | 公開日 | 2008-02-19 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations.
J.Biol.Chem., 283, 2008
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2RLP
 | | NMR structure of CCP modules 1-2 of complement factor H | | 分子名称: | Complement factor H | | 著者 | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | | 登録日 | 2007-07-28 | | 公開日 | 2008-02-19 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations.
J.Biol.Chem., 283, 2008
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2QFG
 | | Solution Structure of the N-terminal SCR-1/5 fragment of Complement Factor H. | | 分子名称: | Complement factor H | | 著者 | Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J. | | 登録日 | 2007-06-27 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
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2QFH
 | | Solution Structure of the C-terminal SCR-16/20 fragment of Complement Factor H. | | 分子名称: | Complement factor H | | 著者 | Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J. | | 登録日 | 2007-06-27 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
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2Q7Z
 | | Solution Structure of the 30 SCR domains of human Complement Receptor 1 | | 分子名称: | Complement receptor type 1 | | 著者 | Furtado, P.B, Huang, C.Y, Ihyembe, D, Hammond, R.A, Marsh, H.C, Perkins, S.J. | | 登録日 | 2007-06-08 | | 公開日 | 2007-10-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The Partly Folded Back Solution Structure Arrangement of the 30 SCR Domains in Human Complement Receptor Type 1 (CR1) Permits Access to its C3b and C4b Ligands
J.Mol.Biol., 375, 2008
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2PSM
 | | Crystal structure of Interleukin 15 in complex with Interleukin 15 receptor alpha | | 分子名称: | BENZAMIDINE, Interleukin-15, Interleukin-15 receptor alpha chain | | 著者 | Olsen, S.K, Murayama, K, Kishishita, S, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Ota, N, Kanagawa, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-05-07 | | 公開日 | 2007-11-06 | | 最終更新日 | 2021-08-18 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal Structure of the Interleukin-15{middle dot}Interleukin-15 Receptor {alpha} Complex: INSIGHTS INTO TRANS AND CIS PRESENTATION
J.Biol.Chem., 282, 2007
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