3GAU

Solution structure of Human Complement Factor H in 50 mM NaCl buffer

Summary for 3GAU

• Entry DOI: 10.2210/pdb3gau/pdb
• Related: 1HAQ 1HFH 2G7I 2IC4 2QFG 2QFH 2RLP 2RLQ 2UWN 3GAV 3GAW
• Descriptor: Complement factor H (1 entity in total)
• Functional Keywords: x-ray solution scattering, complement factor h, scr domain, age-related macular degeneration, complement alternate pathway, disease mutation, glycoprotein, immune response, innate immunity, secreted, sushi, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted: P08603
• Total number of polymer chains: 1
• Total formula weight: 137188.39

Authors

Okemefuna, A.I.,Nan, R.,Gor, J.,Perkins, S.J. (deposition date: 2009-02-18, release date: 2009-06-09, Last modification date: 2024-02-21)

• Primary citation: Okemefuna, A.I.,Nan, R.,Gor, J.,Perkins, S.J.; Electrostatic interactions contribute to the folded-back conformation of wild type human factor H.; J.Mol.Biol., 391:98-118, 2009; PubMed: 19505476; DOI: 10.1016/j.jmb.2009.06.010

Experimental method

SOLUTION SCATTERING