2IC4

Solution structure of the His402 allotype of the Factor H SCR6-SCR7-SCR8 fragment

Summary for 2IC4

• Entry DOI: 10.2210/pdb2ic4/pdb
• Related: 1HAQ
• Descriptor: Complement factor H (1 entity in total)
• Functional Keywords: factor h, x-ray scattering, homology modelling, ultracentrifugation, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P08603
• Total number of polymer chains: 1
• Total formula weight: 21141.78

Authors

Fernando, A.N.,Furtado, P.B.,Gilbert, H.E.,Clark, S.J.,Day, A.J.,Sim, R.B.,Perkins, S.J. (deposition date: 2006-09-12, release date: 2007-04-10, Last modification date: 2024-02-21)

• Primary citation: Fernando, A.N.,Furtado, P.B.,Clark, S.J.,Gilbert, H.E.,Day, A.J.,Sim, R.B.,Perkins, S.J.; Associative and Structural Properties of the Region of Complement Factor H Encompassing the Tyr402His Disease-related Polymorphism and its Interactions with Heparin.; J.Mol.Biol., 368:564-581, 2007; PubMed: 17362990; DOI: 10.1016/j.jmb.2007.02.038

Experimental method

SOLUTION SCATTERING