2RLQ
NMR structure of CCP modules 2-3 of complement factor H
Summary for 2RLQ
| Entry DOI | 10.2210/pdb2rlq/pdb |
| Related | 2BZM 2JGW 2JGX 2RLP |
| Descriptor | Complement factor H (1 entity in total) |
| Functional Keywords | complement, factor h, age-related macular degeneration, immune system, cofactor activity, alternative splicing, complement alternate pathway, disease mutation, glycoprotein, immune response, innate immunity, polymorphism, secreted, sushi |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P08603 |
| Total number of polymer chains | 1 |
| Total formula weight | 14183.70 |
| Authors | Hocking, H.G.,Herbert, A.P.,Pangburn, M.K.,Kavanagh, D.,Barlow, P.N.,Uhrin, D. (deposition date: 2007-07-29, release date: 2008-02-19, Last modification date: 2022-03-16) |
| Primary citation | Hocking, H.G.,Herbert, A.P.,Kavanagh, D.,Soares, D.C.,Ferreira, V.P.,Pangburn, M.K.,Uhrin, D.,Barlow, P.N. Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283:9475-9487, 2008 Cited by PubMed: 18252712DOI: 10.1074/jbc.M709587200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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