3GOV

Crystal structure of the catalytic region of human MASP-1

Summary for 3GOV

Entry DOI	10.2210/pdb3gov/pdb
Descriptor	MASP-1, GLYCEROL, ... (4 entities in total)
Functional Keywords	complement, serine protease, beta barrel, hydrolase, hydroxylation, immune response, innate immunity, sushi, coagulation, complement pathway, disulfide bond, egf-like domain, glycoprotein, protease
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P48740 P48740
Total number of polymer chains	2
Total formula weight	45721.33
Authors	Harmat, V.,Dobo, J.,Beinrohr, L.,Sebestyen, E.,Zavodszky, P.,Gal, P. (deposition date: 2009-03-20, release date: 2009-06-09, Last modification date: 2023-09-06)
Primary citation	Dobo, J.,Harmat, V.,Beinrohr, L.,Sebestyen, E.,Zavodszky, P.,Gal, P. MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity. J.Immunol., 183:1207-1214, 2009 Cited by PubMed: 19564340 DOI: 10.4049/jimmunol.0901141 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation