PDB: 255 件ウェブページステータス検索Chemie searchBIRD

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6ZRV	Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with an Inhibitory Nanobody (VHH-s-a93, Nb93) 分子名称: Plasminogen activator inhibitor 1, VHH-s-a93 (Nb93) 著者 Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. 登録日 2020-07-15 公開日 2020-08-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity. Int J Mol Sci, 21, 2020
6LOS	Crystal structure of mouse PEDF in complex with heterotrimeric collagen model peptide. 分子名称: Collagen model peptide, type I, alpha 1, ... 著者 Kawahara, K, Maruno, T, Oki, H, Yoshida, T, Ohkubo, T, Koide, T, Kobayashi, Y. 登録日 2020-01-07 公開日 2020-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.476 Å) 主引用文献 Spatiotemporal regulation of PEDF signaling by type I collagen remodeling. Proc.Natl.Acad.Sci.USA, 117, 2020
6SSV	The structure of serpin from Schistosoma mansoni 分子名称: Serpin, putative 著者 De Benedetti, S, Gourlay, L. 登録日 2019-09-09 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Structure, Immunoreactivity, and In Silico Epitope Determination of SmSPI S. mansoni Serpin for Immunodiagnostic Application. Vaccines (Basel), 9, 2021
6KGA	Structure of Ovalbumin from Emu (Dromaius novaehollandiae) 分子名称: Ovalbumin 著者 Yasutake, Y, Maehashi, K, Matano, M, Takeuchi, J. 登録日 2019-07-11 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of Emu (Dromaius novaehollandiae) ovalbumin revealed alpha-1-antitrypsin-like domain-swapped trimer. To Be Published
6ROD	Alpha-1-antitrypsin (Ser36Arg/Glu78Arg/Glu266Arg) in the native conformation 分子名称: Alpha-1-antitrypsin 著者 Wan, M, Ronzoni, R, Lomas, D.A, Irving, J.A. 登録日 2019-05-11 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Polymer accumulation in alpha-1 antitrypsin deficiency To Be Published
6IAY	Alpha-1-antitrypsin Queen's (Lys154Asn) variant 分子名称: Alpha-1-antitrypsin, GLYCINE 著者 Aldobiyan, I, Lomas, D.A, Irving, J.A. 登録日 2018-11-28 公開日 2019-12-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural determinants of instability in alpha-1-antitrypsin To Be Published
6I8S	Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1 分子名称: HEAVY CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY, LIGHT CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY, Plasminogen activator inhibitor 1 著者 Vousden, K.A, Lundqvist, T, Popovic, B. 登録日 2018-11-21 公開日 2019-02-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1. Sci Rep, 9, 2019
6I7U	Alpha-1-antitrypsin (Ala250Met) in the native conformation 分子名称: Alpha-1-antitrypsin 著者 Aldobiyan, I, Lomas, D.A, Irving, J.A. 登録日 2018-11-19 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural determinants of instability in alpha-1-antitrypsin To Be Published
6I4V	Alpha-1-antitrypsin Queen's (K154N) variant 分子名称: 3-trimethylsilylpropane-1-sulfonic acid, Alpha-1-antitrypsin, GLYCINE 著者 Aldobiyan, I, Lomas, D.A, Irving, J.A. 登録日 2018-11-12 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural determinants of instability in alpha-1-antitrypsin To Be Published
6I3Z	Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin in complex with its antigen 分子名称: Alpha-1-antitrypsin, Fab 2H2 heavy chain, Fab 2H2 light chain, ... 著者 Laffranchi, M, Elliston, E.L.K, Miranda, E, Perez, J, Jagger, A.M, Fra, A, Lomas, D.A, Irving, J.A. 登録日 2018-11-08 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. JCI Insight, 5, 2020
6I3I	Crystal structure of reactive center loop (RCL) cleaved angiotensinogen 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen 著者 Yan, Y, Read, R.J. 登録日 2018-11-06 公開日 2018-12-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural basis for the specificity of renin-mediated angiotensinogen cleavage. J. Biol. Chem., 294, 2019
6I3F	Crystal structure of the complex of human angiotensinogen and renin at 2.55 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, ... 著者 Yan, Y, Read, R.J. 登録日 2018-11-06 公開日 2018-12-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for the specificity of renin-mediated angiotensinogen cleavage. J. Biol. Chem., 294, 2019
6HX4	Fab fragment of a native monomer-selective antibody in complex with alpha-1-antitrypsin 分子名称: Alpha-1-antitrypsin, Fab 1D9 heavy chain, Fab 1D9 light chain 著者 Elliston, E.L.K, Miranda, E, Perez, J, Jagger, A.M, Lomas, D.A, Irving, J.A. 登録日 2018-10-15 公開日 2019-10-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Characterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin To Be Published
6HGL	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with testosterone 分子名称: Alpha-1-antichymotrypsin, TESTOSTERONE 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGK	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with progesterone 分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, PROGESTERONE 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.855 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGJ	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with aldosterone 分子名称: 1,2-ETHANEDIOL, ALDOSTERONE, Alpha-1-antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.825 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGN	Crystal structure of Alpha1-antichymotrypsin variant DBS-II-allo-L55V: an allosterically controlled doxorubicin-binding serpin with an unprecedentedly high ligand release efficacy 分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.478 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGD	Crystal structure of Alpha1-antichymotrypsin variant NewBG-0: a new binding globulin variant that is devoid of any cortisol-binding capabilities 分子名称: Alpha-1-antichymotrypsin 著者 Gardill, B.R, Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGG	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with cortisol 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.787 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGM	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III-allo: an allosterically controlled new binding globulin with an unprecedentedly high ligand release efficacy 分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CALCIUM ION, ... 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.369 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGF	Crystal structure of Alpha1-antichymotrypsin variant NewBG-II: a new binding globulin in complex with cortisol 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGH	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin without any bound ligand 分子名称: Alpha-1-antichymotrypsin, MALONIC ACID, alpha1-Antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGI	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with corticosterone 分子名称: Alpha-1-antichymotrypsin, CORTICOSTERONE 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.517 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGE	Crystal structure of Alpha1-antichymotrypsin variant NewBG-I in the uncleaved S-conformation 分子名称: Alpha-1-antichymotrypsin 著者 Gardill, B.R, Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6GWQ	Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with an Inhibitory Nanobody (VHH-2g-42) 分子名称: Plasminogen Activator Inhibitor-1, VHH-2g-42 著者 Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. 登録日 2018-06-25 公開日 2020-01-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction. J.Thromb.Haemost., 18, 2020

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