6I3F

Crystal structure of the complex of human angiotensinogen and renin at 2.55 Angstrom

Summary for 6I3F

• Entry DOI: 10.2210/pdb6i3f/pdb
• Descriptor: Angiotensinogen, Renin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: angiotensinogen, renin, glycosylation, complex, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 90445.80

Authors

Yan, Y.,Read, R.J. (deposition date: 2018-11-06, release date: 2018-12-26, Last modification date: 2024-01-24)

• Primary citation: Yan, Y.,Zhou, A.,Carrell, R.W.,Read, R.J.; Structural basis for the specificity of renin-mediated angiotensinogen cleavage.; J. Biol. Chem., 294:2353-2364, 2019; PubMed: 30563843; DOI: 10.1074/jbc.RA118.006608

Experimental method

X-RAY DIFFRACTION (2.55 Å)