6HGM
Crystal structure of Alpha1-antichymotrypsin variant NewBG-III-allo: an allosterically controlled new binding globulin with an unprecedentedly high ligand release efficacy
Summary for 6HGM
Entry DOI | 10.2210/pdb6hgm/pdb |
Descriptor | Alpha-1-antichymotrypsin, CHLORIDE ION, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | serpin, alpha1-antichymotrypsin, computational protein design, allosteric coupling, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 47082.95 |
Authors | Schmidt, K.,Muller, Y.A. (deposition date: 2018-08-23, release date: 2019-05-29, Last modification date: 2024-01-17) |
Primary citation | Gardill, B.R.,Schmidt, K.,Muller, Y.A. NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207:169-182, 2019 Cited by PubMed: 31103428DOI: 10.1016/j.jsb.2019.05.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.369 Å) |
Structure validation
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