6HX4

Fab fragment of a native monomer-selective antibody in complex with alpha-1-antitrypsin

Summary for 6HX4

• Entry DOI: 10.2210/pdb6hx4/pdb
• Related: 6GXX
• Descriptor: Alpha-1-antitrypsin, Fab 1D9 heavy chain, Fab 1D9 light chain, ... (4 entities in total)
• Functional Keywords: antibody fragment, antitrypsin binding, diagnostic, monoclonal, protein binding, conformationally-selective
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 185840.64

Authors

Elliston, E.L.K.,Miranda, E.,Perez, J.,Jagger, A.M.,Lomas, D.A.,Irving, J.A. (deposition date: 2018-10-15, release date: 2019-10-30, Last modification date: 2024-11-13)

• Primary citation: Elliston, E.L.K.,Miranda, E.,Perez, J.,Jagger, A.M.,Irving, J.A.,Lomas, D.A.; Characterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.95 Å)