6HX4
Fab fragment of a native monomer-selective antibody in complex with alpha-1-antitrypsin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alpha-1-antitrypsin | polymer | 397 | 44681.8 | 2 | UniProt (P01009) Pfam (PF00079) | Homo sapiens (Human) | Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
| 2 | C, E (H, I) | Fab 1D9 heavy chain | polymer | 228 | 24379.3 | 2 | Mus musculus | ||
| 3 | D, F (L, M) | Fab 1D9 light chain | polymer | 217 | 23859.3 | 2 | Mus musculus (Mouse) | ||
| 4 | G, H, I (A, B, L) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 394 (UniProt: P01009)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Arg -1 | - | expression tag |
| Gly 0 | Ala 24 | conflict |
| Ser 1 | Glu 25 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 185840.6 | |
| All* | Total formula weight | 185840.6 |
