Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6HGN

Crystal structure of Alpha1-antichymotrypsin variant DBS-II-allo-L55V: an allosterically controlled doxorubicin-binding serpin with an unprecedentedly high ligand release efficacy

Summary for 6HGN
Entry DOI10.2210/pdb6hgn/pdb
DescriptorAlpha-1-antichymotrypsin, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsserpin, alpha1-antichymotrypsin, computational protein design, allosteric coupling, transport protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight46941.34
Authors
Schmidt, K.,Muller, Y.A. (deposition date: 2018-08-23, release date: 2019-05-29, Last modification date: 2024-01-17)
Primary citationGardill, B.R.,Schmidt, K.,Muller, Y.A.
NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207:169-182, 2019
Cited by
PubMed: 31103428
DOI: 10.1016/j.jsb.2019.05.006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.478 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon