PDB: 891 件ウェブページステータス検索Chemie searchBIRD

---

6SXW	Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638) 分子名称: SULFATE ION, Zinc finger protein 638 著者 Newman, J.A, Aitkenhead, H, Wang, D, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-09-26 公開日 2019-10-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.751 Å) 主引用文献 Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638) To Be Published
6SR7	Structure of the U1A variant A1-98 Y31H/Q36R/K98W 分子名称: SULFATE ION, U1 small nuclear ribonucleoprotein A 著者 Rosenbach, H, Span, I. 登録日 2019-09-05 公開日 2020-05-13 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Expanding crystallization tools for nucleic acid complexes using U1A protein variants. J.Struct.Biol., 210, 2020
6SQV	Structure of the U1A variant A1-98 Y31H/Q36R/R70W 分子名称: SULFATE ION, U1 small nuclear ribonucleoprotein A 著者 Rosenbach, H, Span, I. 登録日 2019-09-04 公開日 2020-05-13 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Expanding crystallization tools for nucleic acid complexes using U1A protein variants. J.Struct.Biol., 210, 2020
6SQT	Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant 分子名称: U1 small nuclear ribonucleoprotein A 著者 Rosenbach, H, Span, I. 登録日 2019-09-04 公開日 2020-05-13 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Expanding crystallization tools for nucleic acid complexes using U1A protein variants. J.Struct.Biol., 210, 2020
6SQQ	Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant in complex with RNA obtained by soaking 分子名称: MAGNESIUM ION, RNA hairpin, U1 small nuclear ribonucleoprotein A 著者 Rosenbach, H, Span, I. 登録日 2019-09-04 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Expanding crystallization tools for nucleic acid complexes using U1A protein variants. J.Struct.Biol., 210, 2020
6SQN	Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant co-crystallized with RNA 分子名称: RNA hairpin, U1 small nuclear ribonucleoprotein A 著者 Rosenbach, H, Span, I. 登録日 2019-09-04 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Expanding crystallization tools for nucleic acid complexes using U1A protein variants. J.Struct.Biol., 210, 2020
6SNJ	Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III 分子名称: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER) 著者 Campagne, S, Allain, F.H. 登録日 2019-08-26 公開日 2020-10-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis. Nat Commun, 11, 2020
6SJ7	Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and Indisulam 分子名称: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... 著者 Srinivas, H. 登録日 2019-08-12 公開日 2019-12-18 最終更新日 2019-12-25 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. Nat.Chem.Biol., 16, 2020
6R5K	Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase 分子名称: MAGNESIUM ION, PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAN2-PAN3 deadenylation complex subunit PAN3, ... 著者 Schaefer, I.B, Conti, E. 登録日 2019-03-25 公開日 2019-05-29 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase. Cell, 177, 2019
6QX9	Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Charenton, C, Wilkinson, M.E, Nagai, K. 登録日 2019-03-07 公開日 2019-04-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
6QW6	Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Charenton, C, Wilkinson, M.E, Nagai, K. 登録日 2019-03-05 公開日 2019-04-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
6QDV	Human post-catalytic P complex spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. 登録日 2019-01-03 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science, 363, 2019
6Q2I	Solution state NMR structures of the RNA recognition motif (RRM) domain of human CstF-64 分子名称: Cleavage stimulation factor subunit 2 著者 Latham, M.P, Masoumzadeh, E. 登録日 2019-08-08 公開日 2020-08-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans. Nucleic Acids Res., 48, 2020
6Q0W	Structure of DDB1-DDA1-DCAF15 complex bound to Indisulam and RBM39 分子名称: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... 著者 Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. 登録日 2019-08-02 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
6Q0V	Structure of DDB1-DDA1-DCAF15 complex bound to tasisulam and RBM39 分子名称: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... 著者 Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. 登録日 2019-08-02 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
6Q0R	Structure of DDB1-DDA1-DCAF15 complex bound to E7820 and RBM39 分子名称: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... 著者 Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. 登録日 2019-08-02 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
6PAI	Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and sulfonamide E7820 分子名称: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DDB1- and CUL4-associated factor 15, ... 著者 Volkov, O.A, Du, X. 登録日 2019-06-11 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820. Structure, 27, 2019
6OWJ	Zn-mediated polymerization of human SFPQ 分子名称: Splicing factor, proline- and glutamine-rich, ZINC ION 著者 Lee, M. 登録日 2019-05-10 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ. Nucleic Acids Res., 48, 2020
6NX5	Crystal structure of the RRM domain of S. pombe Puf1 in the P21 space group 分子名称: 1,2-ETHANEDIOL, Pumilio domain-containing protein C56F2.08c 著者 Qiu, C, Hall, T.M.T. 登録日 2019-02-08 公開日 2019-07-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.554 Å) 主引用文献 Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity. Nucleic Acids Res., 47, 2019
6NWW	Crystal structure of the RRM domain of S. pombe Puf1 in the P212121 space group 分子名称: CHLORIDE ION, Pumilio domain-containing protein C56F2.08c 著者 Qiu, C, Hall, T.M.T. 登録日 2019-02-07 公開日 2019-07-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity. Nucleic Acids Res., 47, 2019
6NTY	2.1 A resolution structure of the Musashi-2 (Msi2) RNA recognition motif 1 (RRM1) domain 分子名称: PHOSPHATE ION, RNA-binding protein Musashi homolog 2 著者 Lovell, S, Kashipathy, M.M, Battaile, K.P, Lan, L, Xiaoqing, W, Cooper, A, Gao, F.P, Xu, L. 登録日 2019-01-30 公開日 2019-10-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1. Proteins, 88, 2020
6NSX	Yeast Hsh155 Ligand bound to Human Tat-SF1 Motif 分子名称: CHLORIDE ION, HIV Tat-specific factor 1, Hsh155 著者 Jenkins, J.L, Leach, J.R, Kielkopf, C.L. 登録日 2019-01-25 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction. Rna, 25, 2019
6NCQ	The dimerization domain of human SFPQ in space group C2221 分子名称: Splicing factor, proline- and glutamine-rich 著者 Lee, M. 登録日 2018-12-12 公開日 2019-06-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A new crystal structure and small-angle X-ray scattering analysis of the homodimer of human SFPQ. Acta Crystallogr.,Sect.F, 75, 2019
6N7X	S. cerevisiae U1 snRNP 分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Protein NAM8, ... 著者 Li, X, Liu, S, Jiang, J, Zhang, L, Espinosa, S, Hill, R.C, Hansen, K.C, Zhou, Z.H, Zhao, R. 登録日 2018-11-28 公開日 2019-07-24 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing. Nat Commun, 8, 2017
6N7R	Saccharomyces cerevisiae spliceosomal E complex (ACT1) 分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA, Pre-mRNA-processing factor 39, ... 著者 Liu, S, Li, X, Zhou, Z.H, Zhao, R. 登録日 2018-11-28 公開日 2019-09-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 A unified mechanism for intron and exon definition and back-splicing. Nature, 573, 2019

<567891011121314151617181920>