Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant in complex with RNA obtained by soaking

This is a large structure.

Summary for 6SQQ

DescriptorU1 small nuclear ribonucleoprotein A, RNA hairpin, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsu1 small nuclear ribonucleoprotein a, u1a, rna hairpin, soaking, rna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total molecular weight53995.18
Rosenbach, H.,Span, I. (deposition date: 2019-09-04, release date: 2020-05-13)
Primary citation
Rosenbach, H.,Victor, J.,Borggrafe, J.,Biehl, R.,Steger, G.,Etzkorn, M.,Span, I.
Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210:107480-107480, 2020
PubMed: 32070773 (PDB entries with the same primary citation)
DOI: 10.1016/j.jsb.2020.107480
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.29050 1.2% 0.9% 0.61MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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