6SNJ
Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
Summary for 6SNJ
| Entry DOI | 10.2210/pdb6snj/pdb |
| NMR Information | BMRB: 34427 |
| Descriptor | RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER) (2 entities in total) |
| Functional Keywords | splicing regulation, fus-u1snrnp, spliceosome, splicing |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 23091.82 |
| Authors | Campagne, S.,Allain, F.H. (deposition date: 2019-08-26, release date: 2020-10-28, Last modification date: 2023-06-14) |
| Primary citation | Jutzi, D.,Campagne, S.,Schmidt, R.,Reber, S.,Mechtersheimer, J.,Gypas, F.,Schweingruber, C.,Colombo, M.,von Schroetter, C.,Loughlin, F.E.,Devoy, A.,Hedlund, E.,Zavolan, M.,Allain, F.H.,Ruepp, M.D. Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis. Nat Commun, 11:6341-6341, 2020 Cited by PubMed: 33311468DOI: 10.1038/s41467-020-20191-3 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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