6SNJ

Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Breakpoint for translocation to form FUS/TLS-CHOP oncogene

Chain	Residue	Details
A	GLY267

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site_id	SWS_FT_FI2
Number of Residues	5
Details	MOD_RES: Asymmetric dimethylarginine => ECO:0000269|PubMed:12964758

Chain	Residue	Details
A	GLY260
A	GLY378
A	GLY384
A	GLY387
A	GLY389

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	GLU278

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	ILE287

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	PHE341

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site_id	SWS_FT_FI6
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	GLY335

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