3LRI
 
 | | Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I | | Descriptor: | PROTEIN (INSULIN-LIKE GROWTH FACTOR I) | | Authors: | Laajoki, L.G, Francis, G.L, Wallace, J.C, Carver, J.A, Keniry, M.A. | | Deposit date: | 1999-04-13 | | Release date: | 2000-05-23 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I
J.Biol.Chem., 275, 2000
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1EFE
 | | AN ACTIVE MINI-PROINSULIN, M2PI | | Descriptor: | MINI-PROINSULIN | | Authors: | Cho, Y, Chang, S.G, Choi, K.D, Shin, H, Ahn, B, Kim, K.S. | | Deposit date: | 2000-02-08 | | Release date: | 2000-03-17 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of an Active Mini-Proinsulin, M2PI: Inter-chain Flexibility is Crucial for Insulin Activity
J.Biochem.Mol.Biol., 33, 2000
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5AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE | | Descriptor: | PHENOL, PROTEIN (INSULIN) | | Authors: | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | | Deposit date: | 1998-12-29 | | Release date: | 2000-02-28 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
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3AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, REFINED AVERAGE STRUCTURE | | Descriptor: | PHENOL, PROTEIN (INSULIN) | | Authors: | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | | Deposit date: | 1998-12-29 | | Release date: | 2000-02-28 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
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4AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'GREEN' SUBSTATE, AVERAGE STRUCTURE | | Descriptor: | PHENOL, PROTEIN (INSULIN) | | Authors: | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | | Deposit date: | 1998-12-29 | | Release date: | 2000-02-28 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
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2AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 20 STRUCTURES | | Descriptor: | PHENOL, PROTEIN (INSULIN) | | Authors: | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | | Deposit date: | 1998-12-28 | | Release date: | 2000-02-28 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
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1B9E
 | | HUMAN INSULIN MUTANT SERB9GLU | | Descriptor: | PROTEIN (INSULIN) | | Authors: | Wang, D.C, Zeng, Z.H, Yao, Z.P, Li, H.M. | | Deposit date: | 1998-11-12 | | Release date: | 1999-11-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of an insulin dimer in an orthorhombic crystal: the structure analysis of a human insulin mutant (B9 Ser-->Glu).
Acta Crystallogr.,Sect.D, 55, 1999
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1QIZ
 | | HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH RESORCINOL | | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | | Authors: | Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. | | Deposit date: | 1999-06-18 | | Release date: | 1999-06-22 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis.
Biochemistry, 38, 1999
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1QJ0
 | | HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR | | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | | Authors: | Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. | | Deposit date: | 1999-06-18 | | Release date: | 1999-06-22 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis.
Biochemistry, 38, 1999
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1QIY
 | | HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH PHENOL | | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | | Authors: | Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. | | Deposit date: | 1999-06-18 | | Release date: | 1999-06-22 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis.
Biochemistry, 38, 1999
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1BQT
 | | THREE-DIMENSIONAL STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR-I (IGF-I) DETERMINED BY 1H-NMR AND DISTANCE GEOMETRY, 6 STRUCTURES | | Descriptor: | INSULIN-LIKE GROWTH FACTOR-I | | Authors: | Sato, A, Nishimura, S, Ohkubo, T, Kyogoku, Y, Koyama, S, Kobayashi, M, Yasuda, T, Kobayashi, Y. | | Deposit date: | 1998-08-18 | | Release date: | 1999-05-18 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry.
Int.J.Pept.Protein Res., 41, 1993
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1B9G
 | | INSULIN-LIKE-GROWTH-FACTOR-1 | | Descriptor: | PROTEIN (GROWTH FACTOR IGF-1) | | Authors: | De Wolf, E, Gill, R, Geddes, S, Pitts, J, Wollmer, A, Grotzinger, J. | | Deposit date: | 1999-02-11 | | Release date: | 1999-02-23 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a mini IGF-1.
Protein Sci., 5, 1996
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1ZEI
 | | CROSS-LINKED B28 ASP INSULIN | | Descriptor: | CHLORIDE ION, INSULIN, M-CRESOL, ... | | Authors: | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | | Deposit date: | 1998-07-14 | | Release date: | 1999-02-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
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1IOH
 | | INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES | | Descriptor: | PROTEIN (INSULIN PRECURSOR) | | Authors: | Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. | | Deposit date: | 1998-08-13 | | Release date: | 1999-01-13 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
J.Mol.Biol., 284, 1998
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1IOG
 | | INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES | | Descriptor: | PROTEIN (INSULIN PRECURSOR) | | Authors: | Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. | | Deposit date: | 1998-08-13 | | Release date: | 1999-01-13 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
J.Mol.Biol., 284, 1998
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1ZEH
 | | STRUCTURE OF INSULIN | | Descriptor: | CHLORIDE ION, INSULIN, M-CRESOL, ... | | Authors: | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | | Deposit date: | 1998-05-01 | | Release date: | 1998-12-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
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1A7F
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1ZEG
 | | STRUCTURE OF B28 ASP INSULIN IN COMPLEX WITH PHENOL | | Descriptor: | CHLORIDE ION, INSULIN, PHENOL, ... | | Authors: | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | | Deposit date: | 1998-05-01 | | Release date: | 1998-07-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
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1SJT
 | | MINI-PROINSULIN, TWO CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP, NMR, 20 STRUCTURES | | Descriptor: | PROINSULIN | | Authors: | Hua, Q.X, Hu, S.Q, Jia, W.H, Chu, Y.C, Burke, G.T, Wang, S.H, Katsoyannis, P.G, Weiss, M.A. | | Deposit date: | 1997-10-09 | | Release date: | 1998-03-18 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.
J.Mol.Biol., 277, 1998
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1SJU
 | | MINI-PROINSULIN, SINGLE CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP AND PEPTIDE BOND BETWEEN LYS B 29 AND GLY A 1, NMR, 20 STRUCTURES | | Descriptor: | PROINSULIN | | Authors: | Hua, Q.X, Hu, S.Q, Jia, W.H, Chu, Y.C, Burke, G.T, Wang, S.H, Katsoyannis, P.G, Weiss, M.A. | | Deposit date: | 1997-10-09 | | Release date: | 1998-03-18 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.
J.Mol.Biol., 277, 1998
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1ZNI
 | | INSULIN | | Descriptor: | CHLORIDE ION, INSULIN, ZINC ION | | Authors: | Turkenburg, M.G.W, Whittingham, J.L, Dodson, G.G, Dodson, E.J, Xiao, B, Bentley, G.A. | | Deposit date: | 1997-09-23 | | Release date: | 1998-01-28 | | Last modified: | 2018-07-04 | | Method: | X-RAY DIFFRACTION (1.498 Å) | | Cite: | Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
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1ZNJ
 | | INSULIN, MONOCLINIC CRYSTAL FORM | | Descriptor: | CHLORIDE ION, INSULIN, PHENOL, ... | | Authors: | Turkenburg, M.G.W, Whittingham, J.L, Turkenburg, J.P, Dodson, G.G, Derewenda, U, Smith, G.D, Dodson, E.J, Derewenda, Z.S, Xiao, B. | | Deposit date: | 1997-09-23 | | Release date: | 1998-01-28 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure Determination and Refinement of Two Crystal Forms of Native Insulins
To be Published
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1AI0
 | | R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES | | Descriptor: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | | Authors: | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | | Deposit date: | 1997-04-30 | | Release date: | 1997-11-12 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the R6 human insulin hexamer.
Biochemistry, 36, 1997
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1AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES | | Descriptor: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | | Authors: | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | | Deposit date: | 1997-04-30 | | Release date: | 1997-11-12 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the R6 human insulin hexamer.
Biochemistry, 36, 1997
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1XDA
 | | STRUCTURE OF INSULIN | | Descriptor: | CHLORIDE ION, FATTY ACID ACYLATED INSULIN, MYRISTIC ACID, ... | | Authors: | Whittingham, J.L, Havelund, S, Jonassen, I. | | Deposit date: | 1996-12-18 | | Release date: | 1997-07-07 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of a prolonged-acting insulin with albumin-binding properties.
Biochemistry, 36, 1997
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