PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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6ZI8	X-ray diffraction structure of bovine insulin at 2.3 A resolution 分子名称: CHLORIDE ION, Insulin, ZINC ION 著者 Housset, D, Ling, W.L, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G. 登録日 2020-06-25 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals. Acta Crystallogr D Struct Biol, 77, 2021
5E7W	X-ray Structure of Human Recombinant 2Zn insulin at 0.92 Angstrom 分子名称: ACETATE ION, Insulin, N-PROPANOL, ... 著者 Lisgarten, D.R, Naylor, C.E, Palmer, R.A, Lobley, C.M.C. 登録日 2015-10-13 公開日 2016-10-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (0.9519 Å) 主引用文献 Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K. Chem Cent J, 11, 2017
8GSG	T3R3 form of Human insulin with single Zn 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Zhu, Z.L. 登録日 2022-09-06 公開日 2023-03-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 T3R3 insulin with single Zn To Be Published
5EN9	High resolution x-ray crystal structure of isotope-labeled ester-insulin 分子名称: Insulin chain A, Insulin chain B 著者 Mandal, K, Dhayalan, B, Avital-Shmilovici, M, Tokmakoff, A, Kent, S.B.H. 登録日 2015-11-09 公開日 2016-01-13 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystallization of Enantiomerically Pure Proteins from Quasi-Racemic Mixtures: Structure Determination by X-Ray Diffraction of Isotope-Labeled Ester Insulin and Human Insulin. Chembiochem, 17, 2016
7AC4	Structure of insulin collected by rotation serial crystallography on a COC membrane at a synchrotron source 分子名称: Insulin, R-1,2-PROPANEDIOL, SODIUM ION 著者 Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. 登録日 2020-09-09 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Versatile microporous polymer-based supports for serial macromolecular crystallography. Acta Crystallogr D Struct Biol, 77, 2021
5FB6	Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering 分子名称: Insulin Chain A, Insulin Chain B 著者 Roedig, P, Duman, R, Sanchez-Weatherby, J, Vartiainen, I, Burkhardt, A, Warmer, M, David, C, Wagner, A, Meents, A. 登録日 2015-12-14 公開日 2016-06-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering. J.Appl.Crystallogr., 49, 2016
6ZHB	3D electron diffraction structure of bovine insulin 分子名称: Insulin, ZINC ION 著者 Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G, Ling, W.L, Abrahams, J.P. 登録日 2020-06-22 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 ELECTRON CRYSTALLOGRAPHY (3.25 Å) 主引用文献 Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals. Acta Crystallogr D Struct Biol, 77, 2021
8HSF	Insulin triple mutant INS-RQD 分子名称: Insulin A chain, Insulin B chain 著者 Kundapura, S.V, Rao, S.S, Kulal, A, Ramagopal, U.A. 登録日 2022-12-19 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insulin triple mutant INS-RQD To Be Published
8HSK	Insulin single mutant INS-Q 分子名称: Insulin A chain, Insulin B chain, SULFATE ION 著者 Rao, S.S, Kundapura, S.V, Kulal, A, Ramagopal, U.A. 登録日 2022-12-19 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Insulin single mutant INS-Q To Be Published
8HGZ	Crystal structure of insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2022-11-16 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions Crystals, 13, 2023
5ENA	Xray crystal structure of isotope-labeled human insulin 分子名称: Insulin chain A, Insulin chain B 著者 Mandal, K, Dhayalan, B, Avital-Shmilovici, M, Tokmakoff, A, Kent, S.B.H. 登録日 2015-11-09 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystallization of Enantiomerically Pure Proteins from Quasi-Racemic Mixtures: Structure Determination by X-Ray Diffraction of Isotope-Labeled Ester Insulin and Human Insulin. Chembiochem, 17, 2016
8IPZ	Crystal structure of insulin detemir 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2023-03-15 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of insulin detemir To Be Published
5EMS	Crystal Structure of an iodinated insulin analog 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Lawrence, M.C, Pandyarajan, V, Wan, Z, Weiss, M.A. 登録日 2015-11-06 公開日 2016-11-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY. J. Biol. Chem., 291, 2016
6GV0	Insulin glulisine 分子名称: FORMIC ACID, Insulin, ZINC ION 著者 Chayen, N.E, Helliwell, J.R, Solomon-Gamsu, H.V, Govada, L, Morgan, M, Gillis, R.B, Adams, G. 登録日 2018-06-20 公開日 2019-07-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques. Sci Rep, 11, 2021
3E7Y	Structure of human insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Timofeev, V.I, Baidus, A.N, Kislitsyn, Y.A, Kuranova, I.P. 登録日 2008-08-19 公開日 2009-02-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of human insulin to be published
3P2X	Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. 登録日 2010-10-04 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
3P33	Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. 登録日 2010-10-04 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
3E7Z	Structure of human insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Timofeev, V.I, Lyashenko, A.V, Kislitsyn, Y.A, Baidus, A.N, Kuranova, I.P. 登録日 2008-08-19 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of human insulin To be published
3EXX	Structure of the T6 human insulin derivative with nickel at 1.35 A resolution 分子名称: Insulin A chain, Insulin B chain, NICKEL (II) ION, ... 著者 Prugovecki, B, Matkovic-Calogovic, D. 登録日 2008-10-17 公開日 2009-05-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structure of the T6 Human Nickel Insulin Derivative at 1.35 A Resolution. CROATICA CHEMICA ACTA, 82, 2009
6INS	X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE 分子名称: INSULIN, ZINC ION 著者 Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J. 登録日 1992-11-25 公開日 1994-01-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J.Mol.Biol., 220, 1991
3FHP	A neutron crystallographic analysis of a porcine 2Zn insulin at 2.0 A resolution 分子名称: Insulin, ZINC ION 著者 Iwai, W, Kurihara, K, Yamada, T, Kobayashi, Y, Ohnishi, Y, Tanaka, I, Takahashi, H, Niimura, N. 登録日 2008-12-09 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 NEUTRON DIFFRACTION (2 Å) 主引用文献 A neutron crystallographic analysis of T6 porcine insulin at 2.1 A resolution Acta Crystallogr.,Sect.D, 65, 2009
3RTO	Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure 分子名称: Insulin, ZINC ION 著者 Soares, A.S, Engel, M.A, Stearns, R, Datwani, S, Olechno, J, Ellson, R, Skinner, J.M, Allaire, M, Orville, A.M. 登録日 2011-05-03 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures. Biochemistry, 50, 2011
6JR3	Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body 分子名称: Insulin A chain, Insulin B chain 著者 Sengupta, J, Pathak, B.K, Bhakta, S. 登録日 2019-04-02 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (14.5 Å) 主引用文献 Resveratrol as a nontoxic excipient stabilizes insulin in a bioactive hexameric form. J.Comput.Aided Mol.Des., 34, 2020
3FQ9	Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications 分子名称: Insulin, ZINC ION 著者 Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. 登録日 2009-01-07 公開日 2009-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications. J.Biol.Chem., 284, 2009
6H3M	The crystal structure of a human seleno-insulin analog 分子名称: Insulin 著者 Lansky, S, Weil-Ktorza, O, Metanis, N, Shoham, G. 登録日 2018-07-19 公開日 2019-08-14 最終更新日 2020-08-26 実験手法 X-RAY DIFFRACTION (1.821 Å) 主引用文献 Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin. Chemistry, 25, 2019

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