5EMS

Crystal Structure of an iodinated insulin analog

Summary for 5EMS

• Entry DOI: 10.2210/pdb5ems/pdb
• Descriptor: Insulin, PHENOL, ZINC ION, ... (6 entities in total)
• Functional Keywords: insulin, hormone, non-standard modification, protein design, protein engineering
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 36331.54

Authors

Lawrence, M.C.,Pandyarajan, V.,Wan, Z.,Weiss, M.A. (deposition date: 2015-11-06, release date: 2016-11-16, Last modification date: 2023-11-15)

• Primary citation: El Hage, K.,Pandyarajan, V.,Phillips, N.B.,Smith, B.J.,Menting, J.G.,Whittaker, J.,Lawrence, M.C.,Meuwly, M.,Weiss, M.A.; Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY.; J. Biol. Chem., 291:27023-27041, 2016; PubMed: 27875310; DOI: 10.1074/jbc.M116.761015

Experimental method

X-RAY DIFFRACTION (2.3 Å)