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1MHJ	SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN Descriptor: INSULIN Authors: Jorgensen, A.M.M, Olsen, H.B, Led, J.J, Balschmidt, P. Deposit date: 1994-11-30 Release date: 1995-10-15 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin. J.Mol.Biol., 257, 1996
2BN1	Insulin after a high dose x-ray burn Descriptor: INSULIN A CHAIN, INSULIN B CHAIN Authors: Nanao, M.H, Ravelli, R.B. Deposit date: 2005-03-18 Release date: 2005-09-07 Last modified: 2013-04-03 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
5L3L	D11 bound IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3M	D11 bound [S39_PQ]-IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3N	D11 bound [N29, S39_PQ]-IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
1M5A	Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution Descriptor: COBALT (II) ION, INSULIN A CHAIN, INSULIN B CHAIN Authors: Nicholson, J.M, Perkins, L.C, Korber, F.C. Deposit date: 2002-07-09 Release date: 2002-08-14 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The high-resolution structure of hexameric T6 cobalt insulin: A possible pathway for the T to R transition. Recent Research Developments in Molecular Biology, 3, 2006
2C8Q	insuline(1sec) and UV laser excited fluorescence Descriptor: INSULIN A CHAIN, INSULIN B CHAIN Authors: Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. Deposit date: 2005-12-06 Release date: 2006-03-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
5MIZ	MD ensemble of bovine insulin Descriptor: Insulin Authors: Efimov, S.V, Zgadzay, Y.O, Klochkov, V.V. Deposit date: 2016-11-29 Release date: 2017-01-25 Last modified: 2019-05-08 Method: SOLUTION NMR Cite: MD ensemble of bovine insulin To Be Published
2BN3	Insulin before a high dose x-ray burn Descriptor: INSULIN Authors: Nanao, M.H, Ravelli, R.B. Deposit date: 2005-03-18 Release date: 2005-09-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
5MHD	Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions. Descriptor: Insulin Authors: Bocian, W, Kozerski, L, Bednarek, E, Sitkowski, J. Deposit date: 2016-11-24 Release date: 2017-08-09 Last modified: 2019-05-08 Method: SOLUTION NMR Cite: Structure and pharmaceutical formulation development of a new long-acting recombinant human insulin analog studied by NMR and MS. J Pharm Biomed Anal, 135, 2017
1MSO	T6 Human Insulin at 1.0 A Resolution Descriptor: Insulin A-Chain, Insulin B-Chain, ZINC ION Authors: Smith, G.D, Pangborn, W.A, Blessing, R.H. Deposit date: 2002-09-19 Release date: 2003-03-04 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (1 Å) Cite: The structure of T6 human insulin at 1.0 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
5MAM	Human insulin in complex with serotonin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. Deposit date: 2016-11-03 Release date: 2017-04-05 Last modified: 2017-05-31 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MT9	Human insulin in complex with serotonin and arginine Descriptor: ARGININE, CHLORIDE ION, Insulin, ... Authors: Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. Deposit date: 2017-01-07 Release date: 2017-04-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MT3	Human insulin in complex with serotonin and arginine Descriptor: ARGININE, CHLORIDE ION, Insulin, ... Authors: Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. Deposit date: 2017-01-06 Release date: 2017-04-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
2C8R	insuline(60sec) and UV laser excited fluorescence Descriptor: INSULIN A CHAIN, INSULIN B CHAIN Authors: Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. Deposit date: 2005-12-06 Release date: 2006-03-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
5LIS	Insulin solved by Native SAD from a dataset collected in one second Descriptor: Insulin Authors: Casanas, A, Finke, A, Wang, M. Deposit date: 2016-07-15 Release date: 2016-08-03 Last modified: 2016-09-28 Method: X-RAY DIFFRACTION (2.293 Å) Cite: EIGER detector: application in macromolecular crystallography. Acta Crystallogr D Struct Biol, 72, 2016
5MWQ	Biosynthetic engineered A21K-B31K-B32R human insulin monomer structure in water/acetonitrile solution Descriptor: Insulin Authors: Bocian, W, Kozerski, L. Deposit date: 2017-01-19 Release date: 2018-02-14 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Lysine mis-incorporation at asparagine position during recombinant proteins production in E. coli To Be Published
2A3G	The structure of T6 bovine insulin Descriptor: Insulin, ZINC ION Authors: Smith, G.D, Pangborn, W.A, Blessing, R.H. Deposit date: 2005-06-24 Release date: 2005-10-25 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.25 Å) Cite: The structure of T6 bovine insulin. Acta Crystallogr.,Sect.D, 61, 2005
1OS3	Dehydrated T6 human insulin at 100 K Descriptor: CHLORIDE ION, Insulin, ZINC ION Authors: Smith, G.D, Blessing, R.H. Deposit date: 2003-03-18 Release date: 2003-07-29 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Lessons from an aged, dried crystal of T(6) human insulin. Acta Crystallogr.,Sect.D, 59, 2003
2EFA	Neutron crystal structure of cubic insulin at pD6.6 Descriptor: Insulin Authors: Ishikawa, T, Tanaka, I, Niimura, N. Deposit date: 2007-02-22 Release date: 2008-01-22 Last modified: 2023-10-25 Method: NEUTRON DIFFRACTION (2.7 Å) Cite: A neutron crystallographic analysis of a cubic porcine insulin at pD 6.6 Chem.Phys., 345, 2008
1Q4V	CRYSTAL STRUCTURE OF ALLO-ILEA2-INSULIN, AN INACTIVE CHIRAL ANALOGUE: IMPLICATIONS FOR THE MECHANISM OF RECEPTOR Descriptor: Insulin, PHENOL, ZINC ION Authors: Wan, Z.L, Xu, B, Chu, Y.C, Katsoyannis, P.G, Weiss, M.A. Deposit date: 2003-08-04 Release date: 2003-08-19 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding. Biochemistry, 42, 2003
2AIY	R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 20 STRUCTURES Descriptor: PHENOL, PROTEIN (INSULIN) Authors: O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. Deposit date: 1998-12-28 Release date: 2000-02-28 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
1OS4	Dehydrated T6 human insulin at 295 K Descriptor: Insulin, ZINC ION Authors: Smith, G.D, Blessing, R.H. Deposit date: 2003-03-18 Release date: 2003-07-29 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Lessons from an aged, dried crystal of T(6) human insulin. Acta Crystallogr.,Sect.D, 59, 2003
1PMX	INSULIN-LIKE GROWTH FACTOR-I BOUND TO A PHAGE-DERIVED PEPTIDE Descriptor: IGF-1 ANTAGONIST F1-1, Insulin-like growth factor IB Authors: Skelton, N.J. Deposit date: 2003-06-11 Release date: 2003-10-21 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Complex with a Phage Display-Derived Peptide Provides Insight into the Function of Insulin-like Growth Factor I Biochemistry, 42, 2003
1QIZ	HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH RESORCINOL Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... Authors: Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. Deposit date: 1999-06-18 Release date: 1999-06-22 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38, 1999

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