1Q4V
CRYSTAL STRUCTURE OF ALLO-ILEA2-INSULIN, AN INACTIVE CHIRAL ANALOGUE: IMPLICATIONS FOR THE MECHANISM OF RECEPTOR
Replaces: 1PC1Replaces: 1LW8Summary for 1Q4V
Entry DOI | 10.2210/pdb1q4v/pdb |
Related | 1TRZ |
Descriptor | Insulin, ZINC ION, PHENOL, ... (5 entities in total) |
Functional Keywords | allo-ile-a2-insulin, protein unfolding, insulin receptor, hormone-growth factor complex, hormone/growth factor |
Total number of polymer chains | 4 |
Total formula weight | 11860.23 |
Authors | Wan, Z.L.,Xu, B.,Chu, Y.C.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2003-08-04, release date: 2003-08-19, Last modification date: 2023-08-16) |
Primary citation | Wan, Z.L.,Xu, B.,Chu, Y.C.,Katsoyannis, P.G.,Weiss, M.A. Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding. Biochemistry, 42:12770-12783, 2003 Cited by PubMed: 14596591DOI: 10.1021/bi034430o PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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