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1OW0
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Crystal structure of human FcaRI bound to IgA1-Fc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig alpha-1 chain C region, Immunoglobulin alpha Fc receptor, ...
著者Herr, A.B, Ballister, E.R, Bjorkman, P.J.
登録日2003-03-27
公開日2003-05-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Insights into IgA-mediated immune responses from the crystal structures of human Fc-alpha-RI and its complex with IgA1-Fc
Nature, 423, 2003
4H8W
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BU of 4h8w by Molmil
Crystal structure of non-neutralizing and ADCC-potent antibody N5-i5 in complex with HIV-1 clade A/E gp120 and sCD4.
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, ...
著者Tolbert, W.D, Acharya, P, Kwong, P.D, Pazgier, M.
登録日2012-09-24
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4IM8
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BU of 4im8 by Molmil
low resolution crystal structure of mouse RAGE
分子名称: Advanced glycation end-products receptor
著者Xu, D, Young, J.H, Krahn, J.M, Song, D, Corbett, K.D, Chazin, W.J, Pedersen, L.C, Esko, J.D.
登録日2013-01-02
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction.
Acs Chem.Biol., 8, 2013
5T6Z
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BU of 5t6z by Molmil
KIR3DL1 in complex with HLA-B*57:01-TW10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Decapeptide: THR-SER-THR-LEU-GLN-GLU-GLN-ILE-GLY-TRP, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-02
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
5T89
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BU of 5t89 by Molmil
Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Vascular endothelial growth factor A, ...
著者Markovic-Mueller, S, Stuttfeld, E, Asthana, M, Weinert, T, Bliven, S, Goldie, K.N, Kisko, K, Capitani, G, Ballmer-Hofer, K.
登録日2016-09-07
公開日2017-02-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A.
Structure, 25, 2017
5T70
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KIR3DL1 in complex with HLA-B*57:01 presenting TSNLQEQIGW
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Decapeptide: THR-SER-ASN-LEU-GLN-GLU-GLN-ILE-GLY-TRP, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-02
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
5THR
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BU of 5thr by Molmil
Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex
分子名称: 17b Fab VH domain, 17b Fab VL domain, 8ANC195 G52K5 VH domain, ...
著者Wang, H, Bjorkman, P.J.
登録日2016-09-30
公開日2016-11-16
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.
Proc.Natl.Acad.Sci.USA, 113, 2016
4JM2
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BU of 4jm2 by Molmil
Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab
分子名称: 17b Heavy chain, 17b Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kong, L, Wilson, I.A.
登録日2013-03-13
公開日2013-05-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Nat.Struct.Mol.Biol., 20, 2013
5U1F
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BU of 5u1f by Molmil
Initial contact of HIV-1 Env with CD4: Cryo-EM structure of BG505 DS-SOSIP trimer in complex with CD4 and antibody PGT145
分子名称: BG505 DS-SOSIP gp120, BG505 SOSIP gp41, PGT145 heavy chain, ...
著者Acharya, P, Kwong, P.D, Potter, C.S, Carragher, B.
登録日2016-11-28
公開日2017-02-22
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.
Nat. Struct. Mol. Biol., 24, 2017
5UV6
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BU of 5uv6 by Molmil
Crystal structure of human Opioid Binding Protein/Cell Adhesion Molecule Like (OPCML)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Opioid-binding protein/cell adhesion molecule, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Birtley, J.R, Stern, L.J, Gabra, H, Zanini, E.
登録日2017-02-19
公開日2018-03-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.65002 Å)
主引用文献Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions.
Nat Commun, 10, 2019
5VN3
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BU of 5vn3 by Molmil
Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b
分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ozorowski, G, Pallesen, J, Ward, A.B.
登録日2017-04-28
公開日2017-07-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Nature, 547, 2017
5VI4
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BU of 5vi4 by Molmil
IL-33/ST2/IL-1RAcP ternary complex structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein, Interleukin-1 receptor-like 1, ...
著者Guenther, S, Sundberg, E.J.
登録日2017-04-13
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.792 Å)
主引用文献IL-1 Family Cytokines Use Distinct Molecular Mechanisms to Signal through Their Shared Co-receptor.
Immunity, 47, 2017
4LIQ
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BU of 4liq by Molmil
Structure of the extracellular domain of human CSF-1 receptor in complex with the Fab fragment of RG7155
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment RG7155 heavy chain, Fab fragment RG7155 light chain, ...
著者Benz, J, Gorr, I.H, Hertenberger, H, Ries, C.H.
登録日2013-07-03
公開日2014-06-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
Cancer Cell, 25, 2014
4LP4
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BU of 4lp4 by Molmil
Crystal structure of the human RAGE VC1 fragment in space group P62
分子名称: Advanced glycosylation end product-specific receptor, SODIUM ION
著者Yatime, L, Andersen, G.R.
登録日2013-07-15
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.
Febs J., 280, 2013
4LP5
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BU of 4lp5 by Molmil
Crystal structure of the full-length human RAGE extracellular domain (VC1C2 fragment)
分子名称: Advanced glycosylation end product-specific receptor
著者Yatime, L, Andersen, G.R.
登録日2013-07-15
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.
Febs J., 280, 2013
6U0N
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BU of 6u0n by Molmil
Asymmetrically open conformational state (Class II) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E51 Fab heavy chain, ...
著者Yang, Z, Bjorkman, P.J.
登録日2019-08-14
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody.
Nat.Struct.Mol.Biol., 26, 2019
6TYB
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BU of 6tyb by Molmil
Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Gorman, J, Kwong, P.D.
登録日2019-08-08
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.
Immunity, 51, 2019
6UE7
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BU of 6ue7 by Molmil
Structure of dimeric sIgA complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
登録日2019-09-20
公開日2020-02-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6UEA
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BU of 6uea by Molmil
Structure of pentameric sIgA complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
登録日2019-09-20
公開日2020-02-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6U0L
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BU of 6u0l by Molmil
Asymmetrically open conformational state (Class I) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E51 Fab heavy chain, ...
著者Yang, Z, Bjorkman, P.J.
登録日2019-08-14
公開日2019-12-11
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody.
Nat.Struct.Mol.Biol., 26, 2019
6U7N
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Crystal structure of neurotrimin (NTM)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Neurotrimin, ...
著者Machius, M, Venkannagari, H, Misra, A, Rudenko, G, Rush, S.
登録日2019-09-03
公開日2020-08-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.321 Å)
主引用文献Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.
J.Mol.Biol., 432, 2020
6UE8
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Structure of tetrameric sIgA complex (Class 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
登録日2019-09-20
公開日2020-02-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6UE9
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BU of 6ue9 by Molmil
Structure of tetrameric sIgA complex (Class 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
登録日2019-09-20
公開日2020-02-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6V3J
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BU of 6v3j by Molmil
KIR3DL1 in complex with HLA-B*57:03 presenting the peptide LSSPVTKSF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA-B alpha chain (B*5703GB), ...
著者Maclachlan, B, Rossjohn, J, Vivian, J.P.
登録日2019-11-25
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.
Proc.Natl.Acad.Sci.USA, 117, 2020
2B4C
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BU of 2b4c by Molmil
Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, T-cell surface glycoprotein CD4, ...
著者Huang, C, Tang, M, Zhang, M.Y, Majeed, S, Montabana, E, Stanfield, R.L, Dimitrov, D.S, Korber, B, Sodroski, J, Wilson, I.A, Wyatt, R, Kwong, P.D.
登録日2005-09-23
公開日2005-11-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of a V3-containing HIV-1 gp120 core.
Science, 310, 2005

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