5VI4

IL-33/ST2/IL-1RAcP ternary complex structure

Summary for 5VI4

Entry DOI	10.2210/pdb5vi4/pdb
Descriptor	Interleukin-33, Interleukin-1 receptor-like 1, Interleukin-1 receptor accessory protein, ... (4 entities in total)
Functional Keywords	cytokine, cytokine receptor, signaling, signaling protein
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	6
Total formula weight	185661.45
Authors	Guenther, S.,Sundberg, E.J. (deposition date: 2017-04-13, release date: 2017-09-27, Last modification date: 2023-10-04)
Primary citation	Gunther, S.,Deredge, D.,Bowers, A.L.,Luchini, A.,Bonsor, D.A.,Beadenkopf, R.,Liotta, L.,Wintrode, P.L.,Sundberg, E.J. IL-1 Family Cytokines Use Distinct Molecular Mechanisms to Signal through Their Shared Co-receptor. Immunity, 47:510-523.e4, 2017 Cited by PubMed: 28930661 DOI: 10.1016/j.immuni.2017.08.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.792 Å)

Structure validation