5VI4
IL-33/ST2/IL-1RAcP ternary complex structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005125 | molecular_function | cytokine activity |
| B | 0004908 | molecular_function | interleukin-1 receptor activity |
| C | 0004908 | molecular_function | interleukin-1 receptor activity |
| D | 0005125 | molecular_function | cytokine activity |
| E | 0004908 | molecular_function | interleukin-1 receptor activity |
| F | 0004908 | molecular_function | interleukin-1 receptor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00092 |
| Number of Residues | 7 |
| Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. VITNPPY |
| Chain | Residue | Details |
| B | VAL218-TYR224 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 348 |
| Details | Domain: {"description":"Ig-like C2-type 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Region: {"description":"Flexible linker","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 17 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 32 |
| Details | Region: {"description":"Essential for interaction with PTPRD","evidences":[{"source":"PubMed","id":"25908590","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"25908590","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YFD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
