6U0L

Asymmetrically open conformational state (Class I) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab

Summary for 6U0L

Entry DOI	10.2210/pdb6u0l/pdb
Related	6U0N
EMDB information	20605 20608
Descriptor	Envelope glycoprotein gp120, T-cell surface glycoprotein CD4, E51 Fab heavy chain, ... (9 entities in total)
Functional Keywords	bg505 sosip.664, e51, scd4, env, env open conformation, asymmetrically open env, viral protein
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	15
Total formula weight	429181.70
Authors	Yang, Z.,Bjorkman, P.J. (deposition date: 2019-08-14, release date: 2019-12-11, Last modification date: 2022-02-16)
Primary citation	Yang, Z.,Wang, H.,Liu, A.Z.,Gristick, H.B.,Bjorkman, P.J. Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody. Nat.Struct.Mol.Biol., 26:1167-1175, 2019 Cited by PubMed: 31792452 DOI: 10.1038/s41594-019-0344-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation