PDB: 395 件ウェブページステータス検索Chemie searchBIRD

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7NE1	Structure of the complex between Netrin-1 and its receptor Neogenin 分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. 登録日 2021-02-02 公開日 2021-03-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
3N1P	Crystal Structure of IhhN bound to BOCFn3 分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... 著者 Kavran, J.M, Leahy, D.J. 登録日 2010-05-16 公開日 2010-06-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
7XGD	Cryo-EM structure of Apo-IGF1R map 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor 1 receptor 著者 Zhang, X, Wu, C. 登録日 2022-04-04 公開日 2023-04-12 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of Apo-IGF1R To Be Published
7XLC	conformation II of apo-IGF1R states 分子名称: Insulin-like growth factor 1 receptor 著者 Xi, Z, Cang, W. 登録日 2022-04-21 公開日 2023-04-26 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 conformation II of apo-IGF1R states To Be Published
3NPZ	Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL) 分子名称: Prolactin, Prolactin receptor 著者 Van Agthoven, J, England, P, Goffin, V, Broutin, I. 登録日 2010-06-29 公開日 2010-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone. J.Mol.Biol., 404, 2010
7QID	tentative model of the human insulin receptor ectodomain bound by three insulin 分子名称: Insulin, Insulin receptor, Isoform Short of Insulin receptor 著者 Gutman, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. 登録日 2021-12-14 公開日 2022-02-02 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain J Cell Biol, 219, 2020
7S7K	Crystal structure of the EphB2 extracellular domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, ... 著者 Xu, Y, Xu, K, Nikolov, D.B. 登録日 2021-09-16 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism. Int J Mol Sci, 22, 2021
7SL7	Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R) 分子名称: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ... 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL3	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL1	Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E) 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL4	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL2	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL6	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7S8V	Leg region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... 著者 Xu, Y, Lawrence, M.C. 登録日 2021-09-20 公開日 2022-07-06 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.73 Å) 主引用文献 How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor. Structure, 30, 2022
7S0Q	Head region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... 著者 Xu, Y, Lawrence, M.C. 登録日 2021-08-30 公開日 2022-07-06 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor. Structure, 30, 2022
7STJ	Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 1) 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-14 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STK	Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2) 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-14 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STH	Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-13 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STI	Full-length insulin receptor bound with unsaturated insulin WT (1 insulin bound) asymmetric conformation 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-13 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
4K0V	Structural basis for angiopoietin-1 mediated signaling initiation 分子名称: Angiopoietin-1, TEK tyrosine kinase variant 著者 Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A. 登録日 2013-04-04 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (4.51 Å) 主引用文献 Structural basis for angiopoietin-1-mediated signaling initiation. Proc.Natl.Acad.Sci.USA, 110, 2013
4M4R	Epha4 ectodomain complex with ephrin a5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4, ... 著者 Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B. 登録日 2013-08-07 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.13 Å) 主引用文献 Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5. Proc.Natl.Acad.Sci.USA, 110, 2013
4M4P	Crystal structure of EPHA4 ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4 著者 Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B. 登録日 2013-08-07 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.081 Å) 主引用文献 Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5. Proc.Natl.Acad.Sci.USA, 110, 2013
4MMX	Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ... 著者 van Agthoven, J, Xiong, J, Arnaout, M.A. 登録日 2013-09-09 公開日 2014-03-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin. Nat.Struct.Mol.Biol., 21, 2014
4MMY	Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ... 著者 van Agthoven, J, Xiong, J, Arnaout, M.A. 登録日 2013-09-09 公開日 2014-03-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.183 Å) 主引用文献 Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin. Nat.Struct.Mol.Biol., 21, 2014
4MMZ	Integrin AlphaVBeta3 ectodomain bound to an antagonistic tenth domain of Fibronectin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ... 著者 van Agthoven, J, Xiong, J, Arnaout, M.A. 登録日 2013-09-09 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin. Nat.Struct.Mol.Biol., 21, 2014

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