4K0V

Structural basis for angiopoietin-1 mediated signaling initiation

Summary for 4K0V

• Entry DOI: 10.2210/pdb4k0v/pdb
• Descriptor: TEK tyrosine kinase variant, Angiopoietin-1 (2 entities in total)
• Functional Keywords: cellular signaling, tie receptor tyrosine kinase, signaling protein-transferase complex, signaling protein/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: Q15389
• Total number of polymer chains: 2
• Total formula weight: 85210.04

Authors

Yu, X.,Seegar, T.C.M.,Dalton, A.C.,Tzvetkova-Robev, D.,Goldgur, Y.,Nikolov, D.B.,Barton, W.A. (deposition date: 2013-04-04, release date: 2013-05-08, Last modification date: 2023-09-20)

• Primary citation: Yu, X.,Seegar, T.C.,Dalton, A.C.,Tzvetkova-Robev, D.,Goldgur, Y.,Rajashankar, K.R.,Nikolov, D.B.,Barton, W.A.; Structural basis for angiopoietin-1-mediated signaling initiation.; Proc.Natl.Acad.Sci.USA, 110:7205-7210, 2013; PubMed: 23592718; DOI: 10.1073/pnas.1216890110

Experimental method

X-RAY DIFFRACTION (4.51 Å)