7QID
tentative model of the human insulin receptor ectodomain bound by three insulin
Summary for 7QID
Entry DOI | 10.2210/pdb7qid/pdb |
Related | 6SOF |
EMDB information | 10273 10311 |
Descriptor | Insulin receptor, Isoform Short of Insulin receptor, Insulin, ... (4 entities in total) |
Functional Keywords | cell surface receptor, insulin, tyrosine kinase receptor, glucose homeostasis, hormone, diabetes, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 10 |
Total formula weight | 225810.93 |
Authors | Gutman, T.,Schaefer, I.B.,Poojari, C.S.,Vattulainen, I.,Strauss, M.,Coskun, U. (deposition date: 2021-12-14, release date: 2022-02-02) |
Primary citation | Gutman, T.,Schaefer, I.B.,Poojari, C.S.,Vattulainen, I.,Strauss, M.,Coskun, U. Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain J Cell Biol, 219:-, 2020 Cited by PubMed: 31727777PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5 Å) |
Structure validation
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