7QID

tentative model of the human insulin receptor ectodomain bound by three insulin

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region
F	0005179	molecular_function	hormone activity
F	0005576	cellular_component	extracellular region
I	0005179	molecular_function	hormone activity
I	0005576	cellular_component	extracellular region
J	0005179	molecular_function	hormone activity
J	0005576	cellular_component	extracellular region
K	0005179	molecular_function	hormone activity
K	0005576	cellular_component	extracellular region
L	0005179	molecular_function	hormone activity
L	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCTSiCSlyqLenyC

Chain	Residue	Details
E	CYS6-CYS20

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	386
Details	TOPO_DOM: Extracellular => ECO:0000305

Chain	Residue	Details
B	SER724-LYS917
D	SER724-LYS917

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:2983222

Chain	Residue	Details
B	ASN730
D	ASN730
C	SER373
C	SER380

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
B	ASN743
B	ASN894
D	ASN743
D	ASN894

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973

Chain	Residue	Details
B	ASN881
D	ASN881

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862

Chain	Residue	Details
A	ASN25
A	ASN111
A	ASN255
C	ASN25
C	ASN111
C	ASN255

---

site_id	SWS_FT_FI6
Number of Residues	10
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN78
C	ASN671
A	ASN295
A	ASN606
A	ASN624
A	ASN671
C	ASN78
C	ASN295
C	ASN606
C	ASN624

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:23302862

Chain	Residue	Details
A	ASN215
C	ASN215

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147

Chain	Residue	Details
A	ASN337
A	ASN397
C	ASN337
C	ASN397

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:19349973

Chain	Residue	Details
A	ASN418
C	ASN418

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:1472036, ECO:0000269|PubMed:19159218

Chain	Residue	Details
A	ASN514
C	ASN514

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues
Details	M-CSA 246

Chain

Residue

Details

---

site_id	MCSA2
Number of Residues
Details	M-CSA 246

Chain

Residue

Details

---