6SOF
human insulin receptor ectodomain bound by 4 insulin
Summary for 6SOF
Entry DOI | 10.2210/pdb6sof/pdb |
EMDB information | 10273 |
Descriptor | Insulin receptor, Insulin, ... (4 entities in total) |
Functional Keywords | cell surface receptor, insulin, tyrosine kinase receptor, glucose homeostasis, hormone, diabetes, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 225401.89 |
Authors | Gutmann, T.,Schaefer, I.B.,Poojari, C.S.,Vattulainen, I.,Strauss, M.,Coskun, U. (deposition date: 2019-08-29, release date: 2019-11-13, Last modification date: 2020-05-27) |
Primary citation | Gutmann, T.,Schafer, I.B.,Poojari, C.,Brankatschk, B.,Vattulainen, I.,Strauss, M.,Coskun, U. Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain. J.Cell Biol., 219:-, 2020 Cited by PubMed: 31727777DOI: 10.1083/jcb.201907210 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.3 Å) |
Structure validation
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