6SOF

human insulin receptor ectodomain bound by 4 insulin

Summary for 6SOF

• Entry DOI: 10.2210/pdb6sof/pdb
• EMDB information: 10273
• Descriptor: Insulin receptor, Insulin, ... (4 entities in total)
• Functional Keywords: cell surface receptor, insulin, tyrosine kinase receptor, glucose homeostasis, hormone, diabetes, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 225401.89

Authors

Gutmann, T.,Schaefer, I.B.,Poojari, C.S.,Vattulainen, I.,Strauss, M.,Coskun, U. (deposition date: 2019-08-29, release date: 2019-11-13, Last modification date: 2020-05-27)

• Primary citation: Gutmann, T.,Schafer, I.B.,Poojari, C.,Brankatschk, B.,Vattulainen, I.,Strauss, M.,Coskun, U.; Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain.; J.Cell Biol., 219:-, 2020; PubMed: 31727777; DOI: 10.1083/jcb.201907210

Experimental method

ELECTRON MICROSCOPY (4.3 Å)