1ADZ
 
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1B0C
 | | EVIDENCE OF A COMMON DECAMER IN THREE CRYSTAL STRUCTURES OF BPTI, CRYSTALLIZED FROM THIOCYANATE, CHLORIDE OR SULFATE | | 分子名称: | PROTEIN (PANCREATIC TRYPSIN INHIBITOR) | | 著者 | Hamiaux, C, Prange, T, Ries-Kautt, M, Ducruix, A, Lafont, S, Astier, J.P, Veesler, S. | | 登録日 | 1998-11-06 | | 公開日 | 1998-11-11 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The BPTI decamer observed in acidic pH crystal forms pre-exists as a stable species in solution.
J.Mol.Biol., 297, 2000
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1BIK
 | | X-RAY STRUCTURE OF BIKUNIN FROM THE HUMAN INTER-ALPHA-INHIBITOR COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BIKUNIN, SULFATE ION | | 著者 | Xu, Y, Carr, P.D, Guss, J.M, Ollis, D.L. | | 登録日 | 1997-11-26 | | 公開日 | 1999-03-16 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of bikunin from the inter-alpha-inhibitor complex: a serine protease inhibitor with two Kunitz domains.
J.Mol.Biol., 276, 1998
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1BHC
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1BF0
 | | CALCICLUDINE (CAC) FROM GREEN MAMBA DENDROASPIS ANGUSTICEPS, NMR, 15 STRUCTURES | | 分子名称: | CALCICLUDINE | | 著者 | Gilquin, B, Lecoq, A, Desne, F, Guenneugues, M, Zinn-Justin, S, Menez, A. | | 登録日 | 1998-05-26 | | 公開日 | 1999-01-13 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational and functional variability supported by the BPTI fold: solution structure of the Ca2+ channel blocker calcicludine.
Proteins, 34, 1999
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1BPT
 | | CREVICE-FORMING MUTANTS OF BPTI: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A | | 分子名称: | BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION | | 著者 | Housset, D, Wlodawer, A, Tao, F, Fuchs, J, Woodward, C. | | 登録日 | 1991-12-11 | | 公開日 | 1993-01-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A.
Protein Sci., 2, 1993
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1BPI
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1AAP
 | | X-RAY CRYSTAL STRUCTURE OF THE PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR | | 分子名称: | ALZHEIMER'S DISEASE AMYLOID A4 PROTEIN | | 著者 | Hynes, T.R, Randal, M, Kennedy, L.A, Eigenbrot, C, Kossiakoff, A.A. | | 登録日 | 1990-09-14 | | 公開日 | 1991-10-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor.
Biochemistry, 29, 1990
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1BZ5
 | | EVIDENCE OF A COMMON DECAMER IN THREE CRYSTAL STRUCTURES OF BPTI, CRYSTALLIZE FROM THIOCYANATE, CHLORIDE OR SULFATE | | 分子名称: | PANCREATIC TRYPSIN INHIBITOR, SULFATE ION | | 著者 | Hamiaux, C, Prange, T, Ries-Kautt, M, Ducruix, A, Lafont, S, Astier, J.P, Veesler, S. | | 登録日 | 1998-11-05 | | 公開日 | 1998-11-11 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | The BPTI decamer observed in acidic pH crystal forms pre-exists as a stable species in solution.
J.Mol.Biol., 297, 2000
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1BTI
 | | CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A | | 分子名称: | BOVINE PANCREATIC TRYPSIN INHIBITOR | | 著者 | Housset, D, Tao, F, Kim, K.-S, Fuchs, J, Woodward, C, Wlodawer, A. | | 登録日 | 1991-07-11 | | 公開日 | 1993-10-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A.
Protein Sci., 2, 1993
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3L33
 | | Human mesotrypsin complexed with amyloid precursor protein inhibitor(APPI) | | 分子名称: | Amyloid beta A4 protein, CALCIUM ION, FORMIC ACID, ... | | 著者 | Salameh, M.A, Soares, A.S, Radisky, E.S. | | 登録日 | 2009-12-16 | | 公開日 | 2010-09-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin.
J.Biol.Chem., 285, 2010
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4NTX
 | | Structure of acid-sensing ion channel in complex with snake toxin and amiloride | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE, Acid-sensing ion channel 1, ... | | 著者 | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | | 登録日 | 2013-12-02 | | 公開日 | 2014-02-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
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8OTF
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7V1N
 | | Structure of the Clade 2 C. difficile TcdB in complex with its receptor TFPI | | 分子名称: | Isoform Beta of Tissue factor pathway inhibitor, Toxin B | | 著者 | Luo, J, Yang, Q, Zhang, X, Zhang, Y, Wan, L, Li, Y, Tao, L. | | 登録日 | 2021-08-05 | | 公開日 | 2022-02-23 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile.
Cell, 185, 2022
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3GYM
 | | Structure of Prostasin in Complex with Aprotinin | | 分子名称: | Pancreatic trypsin inhibitor, Prostasin | | 著者 | Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. | | 登録日 | 2009-04-03 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations.
Protein Sci., 18, 2009
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6HAR
 | | Crystal structure of Mesotrypsin in complex with APPI-M17C/I18F/F34C | | 分子名称: | 1,2-ETHANEDIOL, Amyloid-beta A4 protein, CALCIUM ION, ... | | 著者 | Shahar, A, Cohen, I, Radisky, E, Papo, N. | | 登録日 | 2018-08-08 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | | 主引用文献 | Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin.
J.Biol.Chem., 294, 2019
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5C67
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2FI3
 | | Crystal structure of a BPTI variant (Cys14->Ser, Cys38->Ser) in complex with trypsin | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2005-12-27 | | 公開日 | 2006-01-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382, 2008
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4U32
 | | Human mesotrypsin complexed with HAI-2 Kunitz domain 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Kunitz-type protease inhibitor 2, ... | | 著者 | Wang, R, Soares, A.S, Radisky, E.S. | | 登録日 | 2014-07-18 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN.
J.Biol.Chem., 289, 2014
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2FI5
 | | Crystal structure of a BPTI variant (Cys38->Ser) in complex with trypsin | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2005-12-27 | | 公開日 | 2006-01-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382, 2008
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4U30
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6BX8
 | | Human Mesotrypsin (PRSS3) Complexed with Tissue Factor Pathway Inhibitor Variant (TFPI1-KD1-K15R-I17C-I34C) | | 分子名称: | SULFATE ION, Tissue factor pathway inhibitor, Trypsin-3 | | 著者 | Coban, M, Sankaran, B, Cohen, I, Hockla, A, Papo, N, Radisky, E.S. | | 登録日 | 2017-12-18 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin.
J. Biol. Chem., 294, 2019
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6GFI
 | | Structure of Human Mesotrypsin in complex with APPI variant T11V/M17R/I18F/F34V | | 分子名称: | 1,2-ETHANEDIOL, Amyloid-beta A4 protein, PRSS3 protein | | 著者 | Shahar, A, Cohen, I, Radisky, E, Papo, N, Naftaly, S. | | 登録日 | 2018-04-30 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries.
Nat Commun, 9, 2018
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4TPI
 | | THE REFINED 2.2-ANGSTROMS (0.22-NM) X-RAY CRYSTAL STRUCTURE OF THE TERNARY COMPLEX FORMED BY BOVINE TRYPSINOGEN, VALINE-VALINE AND THE ARG15 ANALOGUE OF BOVINE PANCREATIC TRYPSIN INHIBITOR | | 分子名称: | BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, SULFATE ION, ... | | 著者 | Bode, W, Walter, J. | | 登録日 | 1985-06-11 | | 公開日 | 1985-11-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The refined 2.2-A (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor
Eur.J.Biochem., 144, 1984
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4NTW
 | | Structure of acid-sensing ion channel in complex with snake toxin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... | | 著者 | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | | 登録日 | 2013-12-02 | | 公開日 | 2014-02-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
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