PDB: 278 件ウェブページステータス検索Chemie searchBIRD

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4JNE	Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Hsp70 CHAPERONE DnaK, ... 著者 Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. 登録日 2013-03-15 公開日 2013-05-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
4JWD	Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(15-28) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
4JNF	Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP 分子名称: Hsp70 CHAPERONE DnaK 著者 Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. 登録日 2013-03-15 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.621 Å) 主引用文献 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
4JWE	Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(1-21) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
3KVG	Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP 分子名称: 1,2-ETHANEDIOL, Heat shock 70 (HSP70) protein, PHOSPHATE ION, ... 著者 Wernimont, A.K, Hutchinson, A, Sullivan, H, Lew, J, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) 登録日 2009-11-30 公開日 2010-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP To be Published
4JN4	Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ... 著者 Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. 登録日 2013-03-14 公開日 2013-05-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
6ZYI	Crystal structure of HSP70 ATPase domain in complex with ADP and calcium 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Heat shock 70kDa protein 1A variant 著者 Yan, Y, Preissler, S, Ron, D. 登録日 2020-08-01 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9, 2020
4JWI	Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(35-43) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
6ZYJ	Crystal structure of Hsc70 ATPase domain in complex with ADP and calcium 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... 著者 Yan, Y, Preissler, S, Ron, D. 登録日 2020-08-01 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9, 2020
4J8F	Crystal structure of a fusion protein containing the NBD of Hsp70 and the middle domain of Hip 分子名称: ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A/1B, Hsc70-interacting protein, ... 著者 Li, Z, Bracher, A. 登録日 2013-02-14 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle. Nat.Struct.Mol.Biol., 20, 2013
3L4I	CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM Cryptosporidium PARVUM IN COMPLEX WITH ADP and inorganic phosphate 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Pizarro, J.C, Wernimont, A.K, Hutchinson, A, Sullivan, H, Lew, J, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Hills, T, Structural Genomics Consortium (SGC) 登録日 2009-12-20 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM Cryptosporidium PARVUM IN COMPLEX WITH ADP and inorganic phosphate To be Published
7A4V	Crystal structure of lid-truncated ADP-bound BiP in an oligomeric state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Endoplasmic reticulum chaperone BiP, GLYCEROL, ... 著者 Perera, L.A, Ron, D. 登録日 2020-08-20 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9, 2020
6ZYH	Crystal structure of GRP78 (70kDa heat shock protein 5 / BiP) ATPase domain in complex with ADP and calcium 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Endoplasmic reticulum chaperone BiP 著者 Yan, Y, Preissler, S, Ron, D. 登録日 2020-08-01 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9, 2020
4JWC	Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(1-16) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
7A4U	Crystal structure of lid-truncated apo BiP in an oligomeric state 分子名称: Endoplasmic reticulum chaperone BiP, GLYCEROL 著者 Perera, L.A, Ron, D. 登録日 2020-08-20 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9, 2020
3LDN	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in apo form 分子名称: 78 kDa glucose-regulated protein 著者 Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. 登録日 2010-01-13 公開日 2011-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity. J.Med.Chem., 54, 2011
4KBO	Crystal structure of the human Mortalin (GRP75) ATPase domain in the apo form 分子名称: SODIUM ION, Stress-70 protein, mitochondrial 著者 Amick, J, Page, R.C, Nix, J.C, Misra, S. 登録日 2013-04-23 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone. Protein Sci., 23, 2014
3LDP	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with small molecule inhibitor 分子名称: 78 kDa glucose-regulated protein, 8-[(quinolin-2-ylmethyl)amino]adenosine 著者 Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. 登録日 2010-01-13 公開日 2011-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity. J.Med.Chem., 54, 2011
3LDL	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ATP 分子名称: 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. 登録日 2010-01-13 公開日 2011-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity. J.Med.Chem., 54, 2011
3L6Q	Crystal structure of the N-terminal domain of HSP70 from Cryptosporidium parvum (CGD2_20) 分子名称: Heat shock 70 (HSP70) protein, MAGNESIUM ION, SULFATE ION 著者 Pizarro, J.C, Wernimont, A.K, Hutchinson, A, Sullivan, H, Lew, J, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Hills, T, Structural Genomics Consortium (SGC) 登録日 2009-12-24 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Crystal structure of the N-terminal domain of HSP70 from Cryptosporidium parvum (CGD2_20) To be Published
3LDO	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with AMPPNP 分子名称: 78 kDa glucose-regulated protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. 登録日 2010-01-13 公開日 2011-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity. J.Med.Chem., 54, 2011
6CZ1	Crystal structure of ATPase domain of Human GRP78 bound to Ver155008 分子名称: 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, Endoplasmic reticulum chaperone BiP, MAGNESIUM ION 著者 Antoshchenko, T, Chen, Y, Hughes, S, Park, H. 登録日 2018-04-07 公開日 2019-04-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystallographic selection of adenosine analogs that fit the mold of the active site of human GRP78 and beyond To be Published
1ATS	THREONINE 204 OF THE CHAPERONE PROTEIN HSC70 INFLUENCES THE STRUCTURE OF THE ACTIVE SITE BUT IS NOT ESSENTIAL FOR ATP HYDROLYSIS 分子名称: ADENOSINE-5'-DIPHOSPHATE, HEAT-SHOCK COGNATE 70 KD PROTEIN, MAGNESIUM ION 著者 O'Brien, M.C, Mckay, D.B. 登録日 1993-08-09 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Threonine 204 of the chaperone protein Hsc70 influences the structure of the active site, but is not essential for ATP hydrolysis. J.Biol.Chem., 268, 1993
6DFO	Crystal structure of human GRP78 in complex with 8-bromoadenosine 分子名称: 8-bromoadenosine, Endoplasmic reticulum chaperone BiP 著者 Ferrie, R.P, Chen, Y, Antoshchenko, T, Cooney, O.M, Huang, Y, Park, H.W. 登録日 2018-05-15 公開日 2019-05-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Crystal structure of human GRP78 in complex with 8-bromoadenosine To be Published
6DO2	Crystal structure of human GRP78 in complex with 7-deaza-2'-C-methyladenosine 分子名称: 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Endoplasmic reticulum chaperone BiP 著者 Ferrie, R.P, Chen, Y, Antoshchenko, T, Cooney, O.M, Huang, Y, Park, H.W. 登録日 2018-06-08 公開日 2019-06-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human GRP78 in complex with 7-deaza-2'-C-methyladenosine To Be Published

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