6ZYI

Crystal structure of HSP70 ATPase domain in complex with ADP and calcium

Summary for 6ZYI

Entry DOI	10.2210/pdb6zyi/pdb
Descriptor	Heat shock 70kDa protein 1A variant, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (4 entities in total)
Functional Keywords	hsp70, nbd, atpase domain, chaperone, adp
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	42189.49
Authors	Yan, Y.,Preissler, S.,Ron, D. (deposition date: 2020-08-01, release date: 2020-12-16, Last modification date: 2024-01-31)
Primary citation	Preissler, S.,Rato, C.,Yan, Y.,Perera, L.A.,Czako, A.,Ron, D. Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9:-, 2020 Cited by PubMed: 33295873 DOI: 10.7554/eLife.62601 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.52 Å)

Structure validation