6ZYJ

Crystal structure of Hsc70 ATPase domain in complex with ADP and calcium

Summary for 6ZYJ

Entry DOI	10.2210/pdb6zyj/pdb
Descriptor	Heat shock cognate 71 kDa protein, ACETATE ION, CALCIUM ION, ... (6 entities in total)
Functional Keywords	hsc70, nbd, atpase domain, adp, chaperone
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	85009.57
Authors	Yan, Y.,Preissler, S.,Ron, D. (deposition date: 2020-08-01, release date: 2020-12-16, Last modification date: 2024-01-31)
Primary citation	Preissler, S.,Rato, C.,Yan, Y.,Perera, L.A.,Czako, A.,Ron, D. Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9:-, 2020 Cited by PubMed: 33295873 DOI: 10.7554/eLife.62601 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation