6ZYH

Crystal structure of GRP78 (70kDa heat shock protein 5 / BiP) ATPase domain in complex with ADP and calcium

Summary for 6ZYH

Entry DOI	10.2210/pdb6zyh/pdb
Descriptor	Endoplasmic reticulum chaperone BiP, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (4 entities in total)
Functional Keywords	bip, hsp70, grp78, atpase domain, nbd, adp, chaperone
Biological source	Cricetulus griseus (Chinese hamster)
Total number of polymer chains	2
Total formula weight	84751.60
Authors	Yan, Y.,Preissler, S.,Ron, D. (deposition date: 2020-08-01, release date: 2020-12-16, Last modification date: 2024-01-31)
Primary citation	Preissler, S.,Rato, C.,Yan, Y.,Perera, L.A.,Czako, A.,Ron, D. Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9:-, 2020 Cited by PubMed: 33295873 DOI: 10.7554/eLife.62601 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation