PDB: 250 件ウェブページステータス検索Chemie searchBIRD

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5VAR	Crystal structure of KDM4A tandem TUDOR domain in complex with a tri-methyl lysine competitive inhibitor 分子名称: (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol, Lysine-specific demethylase 4A 著者 Judge, R.A, Upadhyay, A.K. 登録日 2017-03-27 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach. Bioorg. Med. Chem. Lett., 28, 2018
5XMY	Crystal structure of TAF3 PHD finger bound to H3K4me3Q5ser 分子名称: Histone peptide H3(1-15)K4me3Q5ser, Transcription initiation factor TFIID subunit 3, ZINC ION 著者 Zhao, S, Zhang, B, Li, H. 登録日 2017-05-16 公開日 2018-11-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Crystal structure of TAF3 PHD finger bound to H3K4me3Q5ser to be published
5WAK	Crystal Structure of a Suz12-Rbbp4 Binary Complex 分子名称: Histone-binding protein RBBP4, Polycomb protein SUZ12, ZINC ION 著者 Chen, S, Jiao, L, Liu, X. 登録日 2017-06-26 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding. Mol. Cell, 69, 2018
5WAI	Crystal Structure of a Suz12-Rbbp4-Jarid2-Aebp2 Heterotetrameric Complex 分子名称: Histone-binding protein RBBP4, Jumonji, AT-rich interactive domain 2, ... 著者 Chen, S, Jiao, L, Liu, X. 登録日 2017-06-26 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding. Mol. Cell, 69, 2018
5XVW	Crystal structure of AL2 PAL domain in complex with AtRing1a distal site 分子名称: AtRing1a distal binding site, PHD finger protein ALFIN-LIKE 2 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-06-28 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5XVL	Crystal structure of AL2 PAL domain 分子名称: PHD finger protein ALFIN-LIKE 2, SULFATE ION 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-06-28 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.629 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5XVJ	Crystal structure of AL7 PAL domain 分子名称: PHD finger protein ALFIN-LIKE 7, SULFATE ION 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-06-28 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5Y20	Crystal structure of AL1 PHD finger bound to H3K4me3 分子名称: PEPTIDE FROM HISTONE H3, PHD finger protein ALFIN-LIKE 1, ZINC ION 著者 Zhao, S, Zhang, B, Li, H. 登録日 2017-07-22 公開日 2018-01-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.409 Å) 主引用文献 Systematic Profiling of Histone Readers in Arabidopsis thaliana. Cell Rep, 22, 2018
5Y21	Crystal structure of AL2 PAL domain in complex with AtRing1a proximal site 分子名称: AtRing1a proximal binding site peptide, PHD finger protein ALFIN-LIKE 2 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-07-22 公開日 2018-07-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.769 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5WLE	Crystal structure of the PPS PHD finger in complex with H3K4me3 分子名称: H3K4me3 Peptide, Protein partner of snf, isoform A, ... 著者 Klein, B.J, Kutateladze, T.G. 登録日 2017-07-26 公開日 2017-10-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.952 Å) 主引用文献 A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO. Structure, 25, 2017
5WLF	Crystal structure of the apo PPS PHD finger 分子名称: GLYCEROL, Protein partner of snf, isoform A, ... 著者 Klein, B.J, Kutateladze, T.G. 登録日 2017-07-26 公開日 2017-10-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO. Structure, 25, 2017
5WMF	Crystal structure of the Hexameric Ring of Epstein-Barr Virus Nuclear Antigen-1, EBNA1 分子名称: Epstein-Barr nuclear antigen 1 著者 Messick, T.E. 登録日 2017-07-28 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance. J. Virol., 91, 2017
5Y53	Crystal structure of AL2 PAL domain in complex with AtBMI1b binding site 分子名称: AtBMI1b binding site, PHD finger protein ALFIN-LIKE 2 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-08-07 公開日 2018-08-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.598 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5Y5W	Crystal structure of human Spindlin1 in complex with a histone H4K20(me3) peptide 分子名称: Histone peptide H4K20(me3), Spindlin-1 著者 Wang, C, Zang, J. 登録日 2017-08-10 公開日 2017-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail FEBS Lett., 592, 2018
5YC4	Crystal structure of AL3 PHD finger bound to H3K4me3 分子名称: Histone H3K4me3, PHD finger protein ALFIN-LIKE 3, ZINC ION 著者 Zhao, S, Zhang, B, Li, H. 登録日 2017-09-06 公開日 2018-01-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.697 Å) 主引用文献 Systematic Profiling of Histone Readers in Arabidopsis thaliana. Cell Rep, 22, 2018
5YKO	Crystal structure of Arabidopsis thaliana JMJ14 catalytic domain in complex with NOG and H3K4me3 peptide 分子名称: H3(1-10)K4me3 peptide, N-OXALYLGLYCINE, NICKEL (II) ION, ... 著者 Yang, Z, Du, J. 登録日 2017-10-15 公開日 2017-12-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases. Plant Cell, 30, 2018
5YKN	crystal structure of Arabidopsis thaliana JMJ14 catalytic domain 分子名称: NICKEL (II) ION, Probable lysine-specific demethylase JMJ14, ZINC ION 著者 Yang, Z, Du, J. 登録日 2017-10-15 公開日 2017-12-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases. Plant Cell, 30, 2018
5YVX	Crystal structure of SDG8 CW domain in complex with H3K4me1 peptide 分子名称: H3K4me1, Histone-lysine N-methyltransferase ASHH2, ZINC ION 著者 Liu, Y, Huang, Y. 登録日 2017-11-27 公開日 2018-03-14 最終更新日 2018-05-09 実験手法 X-RAY DIFFRACTION (1.591 Å) 主引用文献 Uncovering the mechanistic basis for specific recognition of monomethylated H3K4 by the CW domain ofArabidopsishistone methyltransferase SDG8. J. Biol. Chem., 293, 2018
5Z8N	Crystal structure of Arabidopsis thaliana EBS C-terminal deletion construct in complex with an H3K4me2 peptide 分子名称: Chromatin remodeling protein EBS, H3K4me2 peptide, ZINC ION 著者 Yang, Z, Du, J. 登録日 2018-01-31 公開日 2018-07-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat. Genet., 50, 2018
5Z8L	crystal structure of Arabidopsis thaliana EBS in complex with an H3K27me3 peptide 分子名称: Chromatin remodeling protein EBS, H3K27me3 peptide, ZINC ION 著者 Yang, Z, Du, J. 登録日 2018-01-31 公開日 2018-07-25 最終更新日 2018-09-19 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat. Genet., 50, 2018
5ZNR	Crystal structure of PtSHL in complex with an H3K27me3 peptide 分子名称: 17-mer peptide from Histone H3.2, SHORT LIFE family protein, SULFATE ION, ... 著者 Lv, X, Du, J. 登録日 2018-04-10 公開日 2018-07-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.202 Å) 主引用文献 Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL. Nat Commun, 9, 2018
5ZNP	Crystal structure of PtSHL in complex with an H3K4me3 peptide 分子名称: 15-mer peptide from Histone H3.2, SHORT LIFE family protein, ZINC ION 著者 Lv, X, Du, J. 登録日 2018-04-10 公開日 2018-07-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL. Nat Commun, 9, 2018
6E2H	Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30 分子名称: Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2 著者 Joshi, M, Brunzelle, J.S, Couture, J.F. 登録日 2018-07-11 公開日 2018-08-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.236 Å) 主引用文献 Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure, 26, 2018
6I8B	Crystal structure of Spindlin1 in complex with the inhibitor VinSpinIn 分子名称: 2-[4-[2-[[2-[3-[2-azanyl-5-(cyclopropylmethoxy)-3,3-dimethyl-indol-6-yl]oxypropyl]-1,3-dihydroisoindol-5-yl]oxy]ethyl]-1,2,3-triazol-1-yl]-1-[4-(2-pyrrolidin-1-ylethyl)piperidin-1-yl]ethanone, DIMETHYL SULFOXIDE, GLYCINE, ... 著者 Johansson, C, Fagan, V, Brennan, P.E, Sorrell, F.J, Krojer, T, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. 登録日 2018-11-19 公開日 2018-12-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. J.Med.Chem., 62, 2019
6I8L	Crystal structure of Spindlin1 in complex with the inhibitor TD001851a 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-(cyclopropylmethoxy)-6'-[3-(1,3-dihydroisoindol-2-yl)propoxy]spiro[cyclopentane-1,3'-indole]-2'-amine, ... 著者 Johansson, C, Fagan, V, Brennan, P.E, Sorrell, F.J, Krojer, T, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. 登録日 2018-11-20 公開日 2018-12-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. J.Med.Chem., 62, 2019

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