PDB: 155 件ウェブページステータス検索Chemie searchBIRD

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5XVL	Crystal structure of AL2 PAL domain 分子名称: PHD finger protein ALFIN-LIKE 2, SULFATE ION 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-06-28 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.629 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5XVJ	Crystal structure of AL7 PAL domain 分子名称: PHD finger protein ALFIN-LIKE 7, SULFATE ION 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-06-28 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5WFC	Humanized mutant of the Chaetomium thermophilum Polycomb Repressive Complex 2 bound to the inhibitor GSK343 分子名称: Histone H3.1, Histone-lysine-N-methyltransferase EZH2, Polycomb protein SUZ12 chimera, ... 著者 Bratkowski, M.A, Liu, X. 登録日 2017-07-11 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.282 Å) 主引用文献 An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors. Sci Rep, 8, 2018
5WFD	Humanized mutant of the Chaetomium thermophilum Polycomb Repressive Complex 2 bound to the inhibitor GSK126 分子名称: 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide, Histone-lysine-N-methyltransferase EZH2, Polycomb protein SUZ12 chimera, ... 著者 Bratkowski, M.A, Liu, X. 登録日 2017-07-11 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.654 Å) 主引用文献 An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors. Sci Rep, 8, 2018
5WF7	Chaetomium thermophilum Polycomb Repressive Complex 2 bound to GSK126 分子名称: 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide, Histone-lysine-N-methyltransferase EZH2, Polycomb protein SUZ12 chimera, ... 著者 Bratkowski, M.A, Liu, X. 登録日 2017-07-11 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors. Sci Rep, 8, 2018
5WG6	Human Polycomb Repressive Complex 2 in complex with GSK126 inhibitor 分子名称: 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide, Histone-lysine N-methyltransferase EZH2,Polycomb protein SUZ12 (E.C.2.1.1.43) chimera, Polycomb protein EED, ... 著者 Bratkowski, M.A, Liu, X. 登録日 2017-07-13 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.901 Å) 主引用文献 An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors. Sci Rep, 8, 2018
5Y21	Crystal structure of AL2 PAL domain in complex with AtRing1a proximal site 分子名称: AtRing1a proximal binding site peptide, PHD finger protein ALFIN-LIKE 2 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-07-22 公開日 2018-07-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.769 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5WP3	Crystal Structure of EED in complex with EB22 分子名称: EB22, Polycomb protein EED, UNKNOWN ATOM OR ION 著者 Dong, C, Tempel, W, Zhu, L, Moody, J.D, Baker, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2017-08-03 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5Y53	Crystal structure of AL2 PAL domain in complex with AtBMI1b binding site 分子名称: AtBMI1b binding site, PHD finger protein ALFIN-LIKE 2 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-08-07 公開日 2018-08-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.598 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5OY3	The structural basis of the histone demethylase KDM6B histone 3 lysine 27 specificity 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, FE (III) ION, ... 著者 Jones, S.E, Olsen, L, Gajhede, M. 登録日 2017-09-07 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.136 Å) 主引用文献 Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. Biochemistry, 57, 2018
5YUG	AtVAL1 PHD-Like domain in the P31 space group 分子名称: B3 domain-containing transcription repressor VAL1, GLYCEROL, ZINC ION 著者 Zhang, M.M, Wu, B.X. 登録日 2017-11-22 公開日 2018-05-02 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 AtVAL1 PHD-Like domain in the P31 space group To Be Published
6F6D	The catalytic domain of KDM6B in complex with H3(17-33)K18IA21M peptide 分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, Histone 3 peptide H3(17-33)K18IA21M, ... 著者 Jones, S.E, Olsen, L, Gajhede, M. 登録日 2017-12-05 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.81810677 Å) 主引用文献 Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. Biochemistry, 57, 2018
5Z8N	Crystal structure of Arabidopsis thaliana EBS C-terminal deletion construct in complex with an H3K4me2 peptide 分子名称: Chromatin remodeling protein EBS, H3K4me2 peptide, ZINC ION 著者 Yang, Z, Du, J. 登録日 2018-01-31 公開日 2018-07-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat. Genet., 50, 2018
5Z8L	crystal structure of Arabidopsis thaliana EBS in complex with an H3K27me3 peptide 分子名称: Chromatin remodeling protein EBS, H3K27me3 peptide, ZINC ION 著者 Yang, Z, Du, J. 登録日 2018-01-31 公開日 2018-07-25 最終更新日 2018-09-19 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat. Genet., 50, 2018
5ZNP	Crystal structure of PtSHL in complex with an H3K4me3 peptide 分子名称: 15-mer peptide from Histone H3.2, SHORT LIFE family protein, ZINC ION 著者 Lv, X, Du, J. 登録日 2018-04-10 公開日 2018-07-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL. Nat Commun, 9, 2018
5ZNR	Crystal structure of PtSHL in complex with an H3K27me3 peptide 分子名称: 17-mer peptide from Histone H3.2, SHORT LIFE family protein, SULFATE ION, ... 著者 Lv, X, Du, J. 登録日 2018-04-10 公開日 2018-07-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.202 Å) 主引用文献 Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL. Nat Commun, 9, 2018
6A58	Structure of histone demethylase REF6 分子名称: Lysine-specific demethylase REF6, ZINC ION 著者 Tian, Z, Chen, Z. 登録日 2018-06-22 公開日 2019-06-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms. Cell Discov, 6, 2020
6A57	Structure of histone demethylase REF6 complexed with DNA 分子名称: DNA (5'-D(*CP*TP*TP*TP*CP*TP*CP*TP*GP*TP*TP*TP*TP*GP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*AP*AP*AP*AP*CP*AP*GP*AP*GP*AP*AP*A)-3'), GLYCEROL, ... 著者 Tian, Z, Chen, Z. 登録日 2018-06-22 公開日 2019-06-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms. Cell Discov, 6, 2020
6A59	Structure of histone demethylase REF6 at 1.8A 分子名称: Lysine-specific demethylase REF6, ZINC ION 著者 Tian, Z, Chen, Z. 登録日 2018-06-22 公開日 2019-06-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms. Cell Discov, 6, 2020
6IP0	Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with AKG 分子名称: 2-OXOGLUTARIC ACID, NICKEL (II) ION, SULFATE ION, ... 著者 Hu, H, Du, J. 登録日 2018-11-01 公開日 2019-04-10 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor. Nat Commun, 10, 2019
6IP4	Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with NOG and an H3K27me3 peptide 分子名称: Arabidopsis JMJ13, Histone H3.2, N-OXALYLGLYCINE, ... 著者 Hu, H, Du, J. 登録日 2018-11-02 公開日 2019-04-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor. Nat Commun, 10, 2019
6MZM	Human TFIID bound to promoter DNA and TFIIA 分子名称: SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... 著者 Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. 登録日 2018-11-05 公開日 2018-11-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
6MZD	Human TFIID Lobe A canonical 分子名称: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... 著者 Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. 登録日 2018-11-05 公開日 2018-11-28 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (9.8 Å) 主引用文献 Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
6MZL	Human TFIID canonical state 分子名称: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... 著者 Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. 登録日 2018-11-05 公開日 2018-11-28 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (23 Å) 主引用文献 Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
6NQ3	Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex 分子名称: Histone-binding protein RBBP4, PHD finger protein 19, Polycomb protein SUZ12, ... 著者 Chen, S, Jiao, L, Liu, X. 登録日 2019-01-19 公開日 2020-01-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin. Mol.Cell, 77, 2020

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