6F6D
The catalytic domain of KDM6B in complex with H3(17-33)K18IA21M peptide
Summary for 6F6D
| Entry DOI | 10.2210/pdb6f6d/pdb |
| Descriptor | Lysine-specific demethylase 6B, Histone 3 peptide H3(17-33)K18IA21M, FE (III) ION, ... (7 entities in total) |
| Functional Keywords | epigenetics, histone demethylase, substrate based inhibitor, oxidoreductase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 60344.17 |
| Authors | Jones, S.E.,Olsen, L.,Gajhede, M. (deposition date: 2017-12-05, release date: 2018-10-17, Last modification date: 2024-01-17) |
| Primary citation | Jones, S.E.,Olsen, L.,Gajhede, M. Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. Biochemistry, 57:585-592, 2018 Cited by PubMed: 29220567DOI: 10.1021/acs.biochem.7b01152 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.81810675209 Å) |
Structure validation
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