6F6D
The catalytic domain of KDM6B in complex with H3(17-33)K18IA21M peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific demethylase 6B | polymer | 510 | 58050.3 | 1 | UniProt (O15054) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326) | Homo sapiens (Human) | JmjC domain-containing protein 3,Jumonji domain-containing protein 3,Lysine demethylase 6B |
| 2 | B (B) | Histone 3 peptide H3(17-33)K18IA21M | polymer | 17 | 1804.2 | 1 | UniProt (by SIFTS) (P68431) | Homo sapiens | |
| 3 | C (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 6 | F, G, H (A) | TERTIARY-BUTYL ALCOHOL | non-polymer | 74.1 | 3 | Chemie (TBU) | |||
| 7 | I, J (A, B) | water | water | 18.0 | 453 | Chemie (HOH) |
Sequence modifications
A: 1141 - 1643 (UniProt: O15054)
| PDB | External Database | Details |
|---|---|---|
| Met 1140 | - | initiating methionine |
| His 1644 | - | expression tag |
| His 1645 | - | expression tag |
| His 1646 | - | expression tag |
| His 1647 | - | expression tag |
| His 1648 | - | expression tag |
| His 1649 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59854.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 489.7 | |
| All* | Total formula weight | 60344.2 |
