7V1M
 
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7WBX
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3) of the nucleosome | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2021-12-17 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
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7WBV
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-4) of the nucleosome | | 分子名称: | DNA (159-MER), DNA (198-MER), DNA-directed RNA polymerase subunit, ... | | 著者 | Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2021-12-17 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
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7WBW
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3.5) of the nucleosome | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2021-12-17 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
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7XSE
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC42) | | 分子名称: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | 著者 | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2022-05-13 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XSX
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC49) | | 分子名称: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | 著者 | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2022-05-15 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XTD
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) | | 分子名称: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | 著者 | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2022-05-16 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XSZ
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC115) | | 分子名称: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | 著者 | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2022-05-15 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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3ASL
 | | Structure of UHRF1 in complex with histone tail | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ... | | 著者 | Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2010-12-16 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Proc.Natl.Acad.Sci.USA, 109, 2012
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4GNE
 | | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7 | | 分子名称: | Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION | | 著者 | Li, F, He, C, Wu, J, Shi, Y. | | 登録日 | 2012-08-17 | | 公開日 | 2013-01-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
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4GUR
 | | Crystal structure of LSD2-NPAC with H3 in space group P21 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... | | 著者 | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | | 主引用文献 | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
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4GU0
 | | Crystal structure of LSD2 with H3 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3, Lysine-specific histone demethylase 1B, ... | | 著者 | Chen, F, Yang, H, Dong, Z, Fang, J, Zhu, T, Gong, W, Xu, Y. | | 登録日 | 2012-08-29 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.103 Å) | | 主引用文献 | Structural insight into substrate recognition by histone demethylase LSD2/KDM1b
Cell Res., 23, 2013
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4GY5
 | | Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3 | | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION | | 著者 | Cheng, J, Yang, Y, Fang, J, Xiao, J, Zhu, T, Chen, F, Wang, P, Xu, Y. | | 登録日 | 2012-09-05 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.956 Å) | | 主引用文献 | Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
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4GNF
 | | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15 | | 分子名称: | Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION | | 著者 | Li, F, He, C, Wu, J, Shi, Y. | | 登録日 | 2012-08-17 | | 公開日 | 2013-01-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
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4GNG
 | | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide | | 分子名称: | GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase NSD3, ... | | 著者 | Li, F, He, C, Wu, J, Shi, Y. | | 登録日 | 2012-08-17 | | 公開日 | 2013-01-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
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4GUS
 | | Crystal structure of LSD2-NPAC with H3 in space group P3221 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... | | 著者 | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
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6FTX
 | | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin-remodeling ATPase, ... | | 著者 | Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. | | 登録日 | 2018-02-25 | | 公開日 | 2018-08-08 | | 最終更新日 | 2018-10-17 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome.
Elife, 7, 2018
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1M19
 | | LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA | | 分子名称: | 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ... | | 著者 | Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K. | | 登録日 | 2002-06-18 | | 公開日 | 2003-02-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
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6FQ8
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8RBX
 | | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | | 著者 | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | | 登録日 | 2023-12-05 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of Integrator-dependent RNA polymerase II termination.
Nature, 2024
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1M1A
 | | LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA | | 分子名称: | 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ... | | 著者 | Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K. | | 登録日 | 2002-06-18 | | 公開日 | 2003-02-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.MOL.BIOL., 326, 2003
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7W6L
 | | The crystal structure of MLL3-RBBP5-ASH2L in complex with H3K4me0 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W6I
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me1 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W67
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W6J
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me2 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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