1M19

LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA

Summary for 1M19

• Entry DOI: 10.2210/pdb1m19/pdb
• Related: 1AOI 1M18 1M1A
• Descriptor: Palindromic 146 Base Pair DNA Fragment, BETA-ALANINE, 3-AMINO-(DIMETHYLPROPYLAMINE), ... (12 entities in total)
• Functional Keywords: nucleosome, chromatin, histone, pyrrole-imidazole polyamide, dna regognition, chromatin remodeling, structural protein-dna complex, structural protein/dna
• Biological source: Xenopus laevis (African clawed frog); More
• Cellular location: Nucleus: 1M19 P02302 A0A8J1LTD2 P06897
• Total number of polymer chains: 10
• Total formula weight: 206583.70

Authors

Suto, R.K.,Edayathumangalam, R.S.,White, C.L.,Melander, C.,Gottesfeld, J.M.,Dervan, P.B.,Luger, K. (deposition date: 2002-06-18, release date: 2003-02-18, Last modification date: 2023-11-15)

• Primary citation: Suto, R.K.,Edayathumangalam, R.S.,White, C.L.,Melander, C.,Gottesfeld, J.M.,Dervan, P.B.,Luger, K.; Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands; J.Mol.Biol., 326:371-380, 2003; PubMed: 12559907; DOI: 10.1016/S0022-2836(02)01407-9

Experimental method

X-RAY DIFFRACTION (2.3 Å)