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6NHP
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BU of 6nhp by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45T mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2018-12-23
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
Science, 368, 2020
6OI0
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BU of 6oi0 by Molmil
Crystal structure of human WDR5 in complex with L-arginine
Descriptor: ARGININE, GLYCEROL, SULFATE ION, ...
Authors:Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
Deposit date:2019-04-08
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
3O34
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BU of 3o34 by Molmil
Crystal structure of TRIM24 PHD-Bromo complexed with H3(13-32)K23ac peptide
Descriptor: BIOTIN, Histone H3.1, Transcription intermediary factor 1-alpha, ...
Authors:Wang, Z, Patel, D.J.
Deposit date:2010-07-23
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
2R0Y
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BU of 2r0y by Molmil
Structure of the Rsc4 tandem bromodomain in complex with an acetylated H3 peptide
Descriptor: Chromatin structure-remodeling complex protein RSC4, Histone H3 peptide
Authors:VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R.
Deposit date:2007-08-21
Release date:2007-10-30
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
5BT1
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BU of 5bt1 by Molmil
histone chaperone Hif1 playing with histone H2A-H2B dimer
Descriptor: HAT1-interacting factor 1, Histone H2A.1, Histone H2B.1
Authors:Liu, H, Zhang, M, Gao, Y, Teng, M, Niu, L.
Deposit date:2015-06-02
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural Insights into the Association of Hif1 with Histones H2A-H2B Dimer and H3-H4 Tetramer
Structure, 24, 2016
5Y2L
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BU of 5y2l by Molmil
Crystal structure of a group 2 HA binding antibody AF4H1K1 Fab in complex with the 1968 H3N2 pandemic (H3-AC/68) hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Xiao, H, Qi, J, Gao, F.G.
Deposit date:2017-07-26
Release date:2019-01-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins
To Be Published
4EO5
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BU of 4eo5 by Molmil
Yeast Asf1 bound to H3/H4G94P mutant
Descriptor: ACETATE ION, GLYCEROL, Histone H3.2, ...
Authors:Scorgie, J.K, Churchill, M.E.
Deposit date:2012-04-13
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability.
Epigenetics Chromatin, 5, 2012
7VRF
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BU of 7vrf by Molmil
Crystal structure of Oxpecker chromodomain in complex with H3K9me3
Descriptor: H3K9me3, Oxpecker
Authors:Huang, Y, Jin, Z, Yu, B.
Deposit date:2021-10-22
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the chromodomain of Oxpecker in complex with histone H3 lysine 9 trimethylation reveal a transposon silencing mechanism by heterodimerization.
Biochem.Biophys.Res.Commun., 652, 2023
3O35
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BU of 3o35 by Molmil
Crystal structure of TRIM24 PHD-Bromo complexed with H3(23-31)K27ac peptide
Descriptor: Histone H3.1, Transcription intermediary factor 1-alpha, ZINC ION
Authors:Wang, Z, Patel, D.J.
Deposit date:2010-07-23
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
4GUS
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BU of 4gus by Molmil
Crystal structure of LSD2-NPAC with H3 in space group P3221
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ...
Authors:Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUR
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BU of 4gur by Molmil
Crystal structure of LSD2-NPAC with H3 in space group P21
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ...
Authors:Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
1QSR
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BU of 1qsr by Molmil
CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND ACETYL-COENZYME A
Descriptor: ACETYL COENZYME *A, TGCN5 HISTONE ACETYL TRANSFERASE
Authors:Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R.
Deposit date:1999-06-23
Release date:1999-09-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
1QST
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BU of 1qst by Molmil
CRYSTAL STRUCTURE OF TETRAHYMENA GCN5
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGCN5 HISTONE ACETYL TRANSFERASE
Authors:Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R.
Deposit date:1999-06-23
Release date:1999-09-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
5HJB
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BU of 5hjb by Molmil
AF9 YEATS in complex with histone H3 Crotonylation at K9
Descriptor: Protein AF-9, peptide of Histone H3.1
Authors:Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
Deposit date:2016-01-12
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
5HJD
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BU of 5hjd by Molmil
AF9 YEATS in complex with histone H3 Crotonylation at K18
Descriptor: COPPER (II) ION, Protein AF-9, SULFATE ION, ...
Authors:Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
Deposit date:2016-01-13
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016
5HJC
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BU of 5hjc by Molmil
BRD3 second bromodomain in complex with histone H3 acetylation at K18
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ...
Authors:Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
Deposit date:2016-01-13
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
5J9S
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BU of 5j9s by Molmil
ENL YEATS in complex with histone H3 acetylation at K27
Descriptor: H3K27ac peptide from Histone H3.1, Protein ENL, SULFATE ION
Authors:Li, Y, Li, H.
Deposit date:2016-04-11
Release date:2017-03-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia
Nature, 543, 2017
3SOU
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BU of 3sou by Molmil
Structure of UHRF1 PHD finger in complex with histone H3 1-9 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
Authors:Rajakumara, E, Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8001 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
3UII
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BU of 3uii by Molmil
crystal structure of human Survivin in complex with H3(1-10) peptide
Descriptor: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3(1-10) peptide
Authors:Du, J, Patel, D.J.
Deposit date:2011-11-04
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
2YYR
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BU of 2yyr by Molmil
Structural analysis of PHD domain of Pygopus complexed with trimethylated histone H3 peptide
Descriptor: H3K4Me3 peptide, Pygopus homolog 1, ZINC ION
Authors:Nakamura, Y, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-01
Release date:2008-05-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of PHD domain of Pygopus complexed with trimethylated histone H3 peptide
To be Published
5SZB
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BU of 5szb by Molmil
Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with acetylated K14
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
Authors:Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
Deposit date:2016-08-13
Release date:2017-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
7ZMX
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BU of 7zmx by Molmil
Crystal structure of the Plant Homeodomain (PHD) of human ING3
Descriptor: CALCIUM ION, Inhibitor of growth protein 3, ZINC ION
Authors:Ferreras, M.O, Medrano, F.J, Blanco, F.J.
Deposit date:2022-04-20
Release date:2023-05-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural analysis of ING3 protein and histone H3 binding.
Int.J.Biol.Macromol., 242, 2023
5U7G
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BU of 5u7g by Molmil
Crystal Structure of the Catalytic Core of CBP
Descriptor: CREB-binding protein, ZINC ION
Authors:Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E.
Deposit date:2016-12-12
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2F5K
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BU of 2f5k by Molmil
Crystal structure of the chromo domain of human MRG15
Descriptor: Mortality factor 4-like protein 1
Authors:Zhang, P, Du, J, Ding, J.
Deposit date:2005-11-26
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
Nucleic Acids Res., 34, 2006
5VNA
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BU of 5vna by Molmil
Crystal structure of human YEATS domain
Descriptor: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, ...
Authors:Cho, H.J, Cierpicki, T.
Deposit date:2017-04-29
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018

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