5HJC

BRD3 second bromodomain in complex with histone H3 acetylation at K18

Summary for 5HJC

• Entry DOI: 10.2210/pdb5hjc/pdb
• Related: 5HJB 5HJD
• Descriptor: Bromodomain-containing protein 3, peptide of Histone H3.1, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: complex, brd3, bromodomain, histone peptide, acetyllysine, h3k18, signaling protein-peptide complex, signaling protein/peptide
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q15059 P68431
• Total number of polymer chains: 2
• Total formula weight: 14185.85

Authors

Li, Y.Y.,Zhao, D.,Guan, H.P.,Li, H.T. (deposition date: 2016-01-13, release date: 2016-04-20, Last modification date: 2023-11-15)

• Primary citation: Li, Y.Y.,Sabari, B.R.,Panchenko, T.,Wen, H.,Zhao, D.,Guan, H.P.,Wan, L.,Huang, H.,Tang, Z.,Zhao, Y.,Roeder, R.G.,Shi, X.,Allis, C.D.,Li, H.T.; Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain; Mol.Cell, 62:181-193, 2016; PubMed: 27105114; DOI: 10.1016/j.molcel.2016.03.028

Experimental method

X-RAY DIFFRACTION (2.6 Å)